PDB: 13488 件ウェブページステータス検索Chemie searchBIRD

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4DLJ	Human p38 MAP kinase in complex with RL163 分子名称: 2-phenyl-N~4~-(2-phenylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Gruetter, C, Termathe, M. 登録日 2012-02-06 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38alpha kinase. Plos One, 7, 2012
6IAM	Modulating Protein-Protein Interactions with Visible Light Peptide Backbone Switches 分子名称: POTASSIUM ION, SER-ALA-ARG-ALA-XY5-VAL-HIS-LEU-ARG-LYS-SER-ALA, SODIUM ION, ... 著者 Werel, L, Essen, L.-O. 登録日 2018-11-27 公開日 2019-02-06 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Modulating Protein-Protein Interactions with Visible-Light-Responsive Peptide Backbone Photoswitches. Chembiochem, 20, 2019
6XLK	Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPitc-4nt 分子名称: CHAPSO, MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, ... 著者 Yang, Y, Liu, C, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
6XLA	Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPitc-3nt 分子名称: MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, synthetic non-template strand DNA (54-MER), ... 著者 Yang, Y, Liu, C, Shi, W, Liu, B. 登録日 2020-06-28 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
5JHH	Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11 分子名称: 3-{3-[ethyl(quinolin-2-yl)amino]phenyl}propanoic acid, GLYCEROL, Rho guanine nucleotide exchange factor 11, ... 著者 Lv, Z, Wang, R, Ma, L, Miao, Q, Wu, J, Yan, Z, Li, J, Miao, L, Wang, F. 登録日 2016-04-21 公開日 2017-04-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF To Be Published
2RNK	NMR structure of the domain 513-651 of the SARS-CoV nonstructural protein nsp3 分子名称: Replicase polyprotein 1ab 著者 Chatterjee, A, Johnson, M.A, Serrano, P, Pedrini, B, Joseph, J, Saikatendu, K, Neuman, B.W, Wilson, I.A, Stevens, R.C, Buchmeier, M.J, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG) 登録日 2008-01-11 公開日 2008-02-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold. J.Virol., 83, 2009
7VMV	Crystal structure of Dengue NS2B-NS3 Protease after secondary cleavage 分子名称: Core protein 著者 Quek, J.P. 登録日 2021-10-09 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.351 Å) 主引用文献 Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches. Viruses, 14, 2022
1BEV	BOVINE ENTEROVIRUS VG-5-27 分子名称: BOVINE ENTEROVIRUS COAT PROTEINS VP1 TO VP4, MYRISTIC ACID, SULFATE ION 著者 Smyth, M, Tate, J, Lyons, C, Hoey, E, Martin, S, Stuart, D. 登録日 1996-04-03 公開日 1998-09-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Implications for viral uncoating from the structure of bovine enterovirus. Nat.Struct.Biol., 2, 1995
4N4S	A Double Mutant Rat Erk2 in Complex With a Pyrazolo[3,4-d]pyrimidine Inhibitor 分子名称: 3-[2-(benzyloxy)-8-methylquinolin-6-yl]-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Mitogen-activated protein kinase 1 著者 Hari, S.B, Maly, D.J, Merritt, E.A. 登録日 2013-10-08 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases. Chem.Biol., 21, 2014
1HNI	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION 分子名称: (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) 著者 Ding, J, Das, K, Arnold, E. 登録日 1995-02-28 公開日 1995-06-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Structure, 3, 1995
8VGZ	Influenza PA-N Endonuclease E23K Mutant (amino acids 52-74 truncation) 分子名称: MANGANESE (II) ION, Protein PA-X 著者 Kohlbrand, A.J, Cohen, S.M. 登録日 2023-12-30 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry, 63, 2024
6R1U	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... 著者 Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. 登録日 2019-03-15 公開日 2019-04-24 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
6R25	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... 著者 Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. 登録日 2019-03-15 公開日 2019-04-24 実験手法 ELECTRON MICROSCOPY (4.61 Å) 主引用文献 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
2NPQ	A Novel Lipid Binding Site in the p38 alpha MAP Kinase 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Engelberg, D, Livnah, O. 登録日 2006-10-29 公開日 2007-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel lipid binding site formed by the MAP kinase insert in p38 alpha. J.Mol.Biol., 375, 2008
4F0Z	Crystal Structure of Calcineurin in Complex with the Calcineurin-Inhibiting Domain of the African Swine Fever Virus Protein A238L 分子名称: Ankyrin repeat domain-containing protein A238L, CALCIUM ION, Calcineurin subunit B type 1, ... 著者 Grigoriu, S, Peti, W, Page, R. 登録日 2012-05-05 公開日 2013-03-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. Plos Biol., 11, 2013
1CC0	CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... 著者 Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. 登録日 1999-03-03 公開日 2000-01-07 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 How RhoGDI binds Rho. Acta Crystallogr.,Sect.D, 55, 1999
5W44	Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 7a (SRI-29770) 分子名称: 2-[(2S)-1-(2,6-dichlorobenzene-1-carbonyl)pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenylethyl)-1,6-dihydropyrimidine-4-carboxamide, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Kumar, G, White, S.W. 登録日 2017-06-09 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep, 7, 2017
2ERJ	Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Debler, E.W, Stauber, D.J, Wilson, I.A. 登録日 2005-10-25 公開日 2006-02-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor. Proc.Natl.Acad.Sci.Usa, 103, 2006
1VCB	THE VHL-ELONGINC-ELONGINB STRUCTURE 分子名称: PROTEIN (ELONGIN B), PROTEIN (ELONGIN C), PROTEIN (VHL) 著者 Stebbins, C.E, Kaelin, W.G, Pavletich, N.P. 登録日 1999-03-13 公開日 1999-04-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function. Science, 284, 1999
4QJH	Crystal Structure of the Twister Ribozyme with the Nucleotide 5'- to the Cleavage Site Ordered at 4.1 A Resolution 分子名称: MAGNESIUM ION, Twister Ribozyme 著者 Eiler, D.R, Wang, J, Steitz, T.A. 登録日 2014-06-03 公開日 2014-09-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.88 Å) 主引用文献 Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme. Proc.Natl.Acad.Sci.USA, 111, 2014
2BHG	3C protease from type A10(61) foot-and-mouth disease virus 分子名称: FOOT-AND-MOUTH DISEASE VIRUS 3C PROTEASE 著者 Birtley, J.R, Brick, P, Curry, S. 登録日 2005-01-10 公開日 2005-02-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease: New Insights Into Catalytic Mechanism and Cleavage Specificity J.Biol.Chem., 280, 2005
8DW6	T4 bacteriophage primosome with single-strand DNA, State 3 分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (70-MER), DNA primase, ... 著者 Feng, X, Li, H. 登録日 2022-07-31 公開日 2023-06-14 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
1NG0	The three-dimensional structure of Cocksfoot mottle virus at 2.7A resolution 分子名称: CALCIUM ION, coat protein 著者 Tars, K, Zeltins, A, Liljas, L. 登録日 2002-12-16 公開日 2003-02-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The three-dimensional structure of cocksfoot mottle virus at 2.7 A resolution. Virology, 310, 2003
1NHA	Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP-Binding Sites of RAP74 and CTD of RAP74, the subunit of Human TFIIF 分子名称: Transcription initiation factor IIF, alpha subunit 著者 Nguyen, B.D, Chen, H.T, Kobor, M.S, Greenblatt, J, Legault, P, Omichinski, J.G. 登録日 2002-12-19 公開日 2003-02-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB. Biochemistry, 42, 2003
5UK4	VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 分子名称: Anti-vesicular stomatitis virus N VHH, Nucleoprotein, RNA (45-MER) 著者 Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U. 登録日 2017-01-19 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.204 Å) 主引用文献 Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication. EMBO Rep., 18, 2017

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