6R1U

Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2

Summary for 6R1U

Entry DOI	10.2210/pdb6r1u/pdb
EMDB information	4705
Descriptor	Histone H3.2, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (11 entities in total)
Functional Keywords	histone demethylation, chromatin reader, flavoenzyme, epigenetics, evolution of protein function, molecular recognition., gene regulation
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	13
Total formula weight	315756.66
Authors	Marabelli, C.,Pilotto, S.,Chittori, S.,Subramaniam, S.,Mattevi, A. (deposition date: 2019-03-15, release date: 2019-04-24, Last modification date: 2019-10-30)
Primary citation	Marabelli, C.,Marrocco, B.,Pilotto, S.,Chittori, S.,Picaud, S.,Marchese, S.,Ciossani, G.,Forneris, F.,Filippakopoulos, P.,Schoehn, G.,Rhodes, D.,Subramaniam, S.,Mattevi, A. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27:387-399.e7, 2019 Cited by PubMed: 30970244 DOI: 10.1016/j.celrep.2019.03.061 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.36 Å)

Structure validation