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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6R1U

Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, EHistone H3.2polymer13515303.92UniProt (P84233)
Pfam (PF00125)
In PDB		Xenopus laevis (African clawed frog)
2B, FHistone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
In PDB		Xenopus laevis (African clawed frog)
3C, GHistone H2Apolymer12913978.22UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
In PDB		Xenopus laevis (African clawed frog)
4D, HHistone H2B 1.1polymer12213524.82UniProt (P02281)
Pfam (PF00125)
In PDB		Xenopus laevis (African clawed frog)H2B1.1
5IDNA (147-MER)polymer14745610.01synthetic construct
6JDNA (147-MER)polymer14745138.81synthetic construct
7KLysine-specific histone demethylase 1Bpolymer77687051.51UniProt (Q8NB78)
Pfam (PF07496)
Pfam (PF04433)
Pfam (PF01593)
In PDB		Homo sapiens (Human)Flavin-containing amine oxidase domain-containing protein 1,Lysine-specific histone demethylase 2
8LPutative oxidoreductase GLYR1polymer12413528.31UniProt (Q49A26)
In PDB		Homo sapiens (Human)3-hydroxyisobutyrate dehydrogenase-like protein,Cytokine-like nuclear factor N-PAC,Glyoxylate reductase 1 homolog,Nuclear protein NP60,Nuclear protein of 60 kDa
9MHistone H3polymer13515305.91UniProt (A0A310TTQ1)
Pfam (PF00125)
UniProt (by SIFTS) (P84233)
In PDB		Xenopus laevis (African clawed frog)
10KFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
11KZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
PDBExternal DatabaseDetails
Ala 102Gly 103conflict
D, H: 1 - 122 (UniProt: P02281)
PDBExternal DatabaseDetails
Thr 29Ser 33conflict
K: 51 - 822 (UniProt: Q8NB78)
PDBExternal DatabaseDetails
Pro 47-expression tag
Leu 48-expression tag
Gly 49-expression tag
Ser 50-expression tag
L: 152 - 268 (UniProt: Q49A26)
PDBExternal DatabaseDetails
Pro 145-expression tag
Leu 146-expression tag
Gly 147-expression tag
Ser 148-expression tag
Pro 149-expression tag
Glu 150-expression tag
Phe 151-expression tag
M: 1 - 135 (UniProt: A0A310TTQ1)
PDBExternal DatabaseDetails
Met 4Lys 5conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight314774.9
Non-Polymers*Number of molecules4
Total formula weight981.8
All*Total formula weight315756.7
*Water molecules are not included.

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PDB entries from 2024-04-24

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