5UK4

VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307

Summary for 5UK4

DescriptorNucleoprotein, Anti-vesicular stomatitis virus N VHH, RNA (45-MER) (3 entities in total)
Functional Keywordsvesicular stomatitis virus, nucleoprotein, inhibitory vhh, antiviral, viral protein-rna-immune system complex, viral protein/rna/immune system
Biological sourceVesicular stomatitis Indiana virus (strain San Juan) (VSIV)
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Total number of polymer chains44
Total molecular weight1309767.21
Authors
Hanke, L.,Knockenhauer, K.E.,Ploegh, H.L.,Schwartz, T.U. (deposition date: 2017-01-19, release date: 2017-04-19, Last modification date: 2020-02-26)
Primary citation
Hanke, L.,Schmidt, F.I.,Knockenhauer, K.E.,Morin, B.,Whelan, S.P.,Schwartz, T.U.,Ploegh, H.L.
Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep., 18:1027-1037, 2017
PubMed: 28396572 (PDB entries with the same primary citation)
DOI: 10.15252/embr.201643764
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.204 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2889 0.3% 1.0% 0.3% 0.46MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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167327
PDB entries from 2020-08-05