1HNI
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION
Summary for 1HNI
Entry DOI | 10.2210/pdb1hni/pdb |
Descriptor | HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE (3 entities in total) |
Functional Keywords | nucleotidyltransferase |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03367 |
Total number of polymer chains | 2 |
Total formula weight | 114624.06 |
Authors | Ding, J.,Das, K.,Arnold, E. (deposition date: 1995-02-28, release date: 1995-06-03, Last modification date: 2024-02-07) |
Primary citation | Ding, J.,Das, K.,Tantillo, C.,Zhang, W.,Clark Jr., A.D.,Jessen, S.,Lu, X.,Hsiou, Y.,Jacobo-Molina, A.,Andries, K.,Pauwels, R.,Moereels, H.,Koymans, L.,Janssen, P.A.J.,Smith Jr., R.H.,Koepke, M.K.,Michejda, C.J.,Hughes, S.H.,Arnold, E. Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Structure, 3:365-379, 1995 Cited by PubMed: 7542140DOI: 10.1016/S0969-2126(01)00168-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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