6IAM

Modulating Protein-Protein Interactions with Visible Light Peptide Backbone Switches

Summary for 6IAM

Entry DOI	10.2210/pdb6iam/pdb
Descriptor	WD repeat-containing protein 5, SER-ALA-ARG-ALA-XY5-VAL-HIS-LEU-ARG-LYS-SER-ALA, Small ubiquitin-related modifier 5, ... (6 entities in total)
Functional Keywords	histone modification, trimethylation at 'lys-4', epigenetic transcriptional activation, nsl complex, osteoblasts differentiation, leukemia, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	35759.73
Authors	Werel, L.,Essen, L.-O. (deposition date: 2018-11-27, release date: 2019-02-06, Last modification date: 2023-11-15)
Primary citation	Albert, L.,Penalver, A.,Djokovic, N.,Werel, L.,Hoffarth, M.,Ruzic, D.,Xu, J.,Essen, L.O.,Nikolic, K.,Dou, Y.,Vazquez, O. Modulating Protein-Protein Interactions with Visible-Light-Responsive Peptide Backbone Photoswitches. Chembiochem, 20:1417-1429, 2019 Cited by PubMed: 30675988 DOI: 10.1002/cbic.201800737 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.51 Å)

Structure validation