PDB: 214399 件ウェブページステータス検索Chemie searchBIRD

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1MV3	NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC 分子名称: Myc box dependent interacting protein 1 著者 Pineda-Lucena, A, Arrowsmith, C.H. 登録日 2002-09-24 公開日 2003-09-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J.Mol.Biol., 351, 2005
1MUZ	NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC 分子名称: Myc box dependent interacting protein 1 著者 Pineda-Lucena, A, Arrowsmith, C.H. 登録日 2002-09-24 公開日 2003-09-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J.Mol.Biol., 351, 2005
1CK1	STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN C3 分子名称: PROTEIN (ENTEROTOXIN TYPE C-3), ZINC ION 著者 Chi, Y.-I, Bohach, G.A, Stauffacher, C.V. 登録日 1999-04-26 公開日 2002-07-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Zinc-mediated dimerization and its effect on activity and conformation of staphylococcal enterotoxin type C. J.Biol.Chem., 277, 2002
5PZM	CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[2-(4-FLUOROPHENYL)-3-(METHYLCARBAMOYL)-1-BENZOFURAN-5-YL]BENZOIC ACID 分子名称: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, 3-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-5-yl]benzoic acid, GLYCEROL, ... 著者 Sheriff, S. 登録日 2017-02-27 公開日 2017-05-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J. Med. Chem., 60, 2017
3FRY	Crystal structure of the CopA C-terminal metal binding domain 分子名称: CITRIC ACID, Probable copper-exporting P-type ATPase A 著者 Agarwal, S, Sazinsky, M, Arguello, J, Rosenzweig, A.C. 登録日 2009-01-08 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA. Proteins, 78, 2010
2YKI	Tricyclic series of Hsp90 inhibitors 分子名称: 1-H-PYRROLO[2,3-B]PYRIDINE-4-CARBOXYLIC ACID [4-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-9H-FLUOREN-9-YL]-AMIDE, HEAT SHOCK PROTEIN HSP 90-ALPHA 著者 Dupuy, A, Vallee, F. 登録日 2011-05-27 公開日 2011-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-C]Pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 54, 2011
1LBK	Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ... 著者 Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M. 登録日 2002-04-04 公開日 2002-04-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences. J.Mol.Biol., 325, 2003
6BNA	BINDING OF AN ANTITUMOR DRUG TO DNA. NETROPSIN AND C-G-C-G-A-A-T-T-BRC-G-C-G 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(CBR)P*GP*CP*G)-3'), NETROPSIN 著者 Kopka, M.L, Yoon, C, Goodsell, D, Pjura, P, Dickerson, R.E. 登録日 1984-08-30 公開日 1984-10-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Binding of an antitumor drug to DNA, Netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G. J.Mol.Biol., 183, 1985
5TRY	Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2206 分子名称: (2~{S})-~{N}-[(2~{S})-3-methoxy-1-(naphthalen-1-ylmethylamino)-1-oxidanylidene-propan-2-yl]-4-oxidanylidene-2-(3-phenylpropanoylamino)-4-piperidin-1-yl-butanamide, Proteasome subunit alpha, Proteasome subunit beta 著者 Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. 登録日 2016-10-27 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.000008 Å) 主引用文献 Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56, 2017
5TS0	Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2208 分子名称: (2S)-N-{(2S)-3-methoxy-1-[(naphthalen-1-ylmethyl)amino]-1-oxopropan-2-yl}-4-oxo-2-[(3-phenylpropanoyl)amino]-4-(1H-pyrrol-1-yl)butanamide (non-preferred name), Proteasome subunit alpha, Proteasome subunit beta 著者 Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. 登録日 2016-10-27 公開日 2017-01-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.84679747 Å) 主引用文献 Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56, 2017
4BH6	Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex 分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 著者 He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. 登録日 2013-03-29 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
100D	CRYSTAL STRUCTURE OF THE HIGHLY DISTORTED CHIMERIC DECAMER R(C)D(CGGCGCCG)R(G)-SPERMINE COMPLEX-SPERMINE BINDING TO PHOSPHATE ONLY AND MINOR GROOVE TERTIARY BASE-PAIRING 分子名称: DNA/RNA (5'-R(*CP*)-D(*CP*GP*GP*CP*GP*CP*CP*GP*)-R(*G)-3'), SPERMINE 著者 Ban, C, Ramakrishnan, B, Sundaralingam, M. 登録日 1994-12-05 公開日 1995-03-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the highly distorted chimeric decamer r(C)d(CGGCGCCG)r(G).spermine complex--spermine binding to phosphate only and minor groove tertiary base-pairing. Nucleic Acids Res., 22, 1994
2YCC	OXIDATION STATE-DEPENDENT CONFORMATIONAL CHANGES IN CYTOCHROME C 分子名称: CYTOCHROME C, HEME C, SULFATE ION 著者 Berghuis, A.M, Brayer, G.D. 登録日 1991-01-29 公開日 1992-07-15 最終更新日 2021-03-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Oxidation state-dependent conformational changes in cytochrome c. J.Mol.Biol., 223, 1992
7CLZ	Crystal structure of Alp1U W187F/Y247F in complex with fluostatin C 分子名称: BORIC ACID, D-MALATE, Fluostatin C, ... 著者 Zhang, L, De, B.C. 登録日 2020-07-22 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.10001016 Å) 主引用文献 Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295, 2020
161D	A SINGLE 2'-HYDROXYL GROUP CONVERTS B-DNA TO A-DNA: CRYSTAL STRUCTURE OF THE DNA-RNA CHIMERIC DECAMER DUPLEX D(CCGGC)R(G)D(CCGG) WITH A NOVEL INTERMOLECULAR G.C BASE-PAIRED QUADRUPLET 分子名称: DNA/RNA (5'-D(*CP*CP*GP*GP*CP*)-R(*GP*)-D(*CP*CP*GP*G)-3') 著者 Ban, C, Ramakrishnan, B, Sundaralingam, M. 登録日 1994-02-10 公開日 1994-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A single 2'-hydroxyl group converts B-DNA to A-DNA. Crystal structure of the DNA-RNA chimeric decamer duplex d(CCGGC)r(G)d(CCGG) with a novel intermolecular G-C base-paired quadruplet. J.Mol.Biol., 236, 1994
4AC8	R2-like ligand binding Mn-Fe oxidase from M. tuberculosis with an organized C-terminal helix 分子名称: CALCIUM ION, FE (III) ION, GLYCEROL, ... 著者 Andersson, C.S, Berthold, C.L, Hogbom, M. 登録日 2011-12-14 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 A Dynamic C-Terminal Segment in the Mycobacterium Tuberculosis Mn/Fe R2Lox Protein Can Adopt a Helical Structure with Possible Functional Consequences. Chem.Biodivers., 9, 2012
7VBT	Crystal structure of RIOK2 in complex with CQ211 分子名称: 8-(6-methoxypyridin-3-yl)-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]-5H-[1,2,3]triazolo[4,5-c]quinolin-4-one, Serine/threonine-protein kinase RIO2 著者 Zhu, C, Zhang, Z.M. 登録日 2021-09-01 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.54001474 Å) 主引用文献 Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro- 4H -[1,2,3]triazolo[4,5- c ]quinolin-4-one (CQ211) as a Highly Potent and Selective RIOK2 Inhibitor. J.Med.Chem., 65, 2022
1KNK	Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis 分子名称: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MANGANESE (II) ION 著者 Richard, S.B, Ferrer, J.L, Bowman, M.E, Lillo, A.M, Tetzlaff, C.N, Cane, D.E, Noel, J.P. 登録日 2001-12-18 公開日 2002-06-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. J.Biol.Chem., 277, 2002
7VU7	The Solution structure of the C-terminal domain from flagelliform spidroin 分子名称: Flagelliform fibroin 著者 Fan, J.S, Yang, D. 登録日 2021-11-01 公開日 2022-04-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 C-Terminal Domains of Spider Silk Proteins Having Divergent Structures but Conserved Functional Roles. Biomacromolecules, 23, 2022
2ZJO	Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor 分子名称: Genome polyprotein, N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM 著者 Liaw, S.H, Chen, S.J, Hu, C.Y, Chi, W.K, Chu, I.D, Hwang, L.H, Chern, J.W, Chen, D.S. 登録日 2008-03-07 公開日 2009-03-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Discovery of Triphenylmethane Derivatives as Novel Inhibitors of Hepatitis C Virus Helicase To be Published
1W87	FERREDOXIN-NADP REDUCTASE (MUTATION: Y 303 W) COMPLEXED WITH NADP BY COCRYSTALLIZATION 分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hermoso, J.A, Perez-Dorado, I, Maya, C. 登録日 2004-09-16 公開日 2005-10-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H. Biochemistry, 44, 2005
8U0G	Full-length dimer of DNA-Damage Response Protein C from Deinococcus radiodurans - Crystal form xMJ7124 分子名称: DNA damage response protein C 著者 Szabla, R, Li, M.C, Junop, M.S. 登録日 2023-08-29 公開日 2023-09-06 実験手法 X-RAY DIFFRACTION (4.28 Å) 主引用文献 Full-length dimer of DNA-Damage Response Protein C from Deinococcus radiodurans To Be Published
2XI3	HCV-H77 NS5B Polymerase Complexed With GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA-directed RNA polymerase 著者 Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. 登録日 2010-06-25 公開日 2010-08-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
1W34	FERREDOXIN-NADP REDUCTASE (MUTATION: Y 303 S) 分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION 著者 Hermoso, J.A, Perez-Dorado, I, Medina, M, Julvez, M.M, Sanz-Aparicio, J, Gomez-Moreno, C. 登録日 2004-07-13 公開日 2005-10-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H. Biochemistry, 44, 2005
6LUS	Crystal structure of the Mengla Virus VP30 C-terminal domain 分子名称: Minor nucleoprotein VP30 著者 Dong, S.S, Wen, K.N, Chu, H.G, Wang, C.H, Qin, X.C. 登録日 2020-01-30 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the Mengla virus VP30 C-terminal domain. Biochem.Biophys.Res.Commun., 525, 2020

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