3N3T

Crystal structure of putative diguanylate cyclase/phosphodiesterase complex with cyclic di-gmp

Replaces:  3II8

Summary for 3N3T

• Entry DOI: 10.2210/pdb3n3t/pdb
• Related: 2R6o
• Descriptor: PUTATIVE DIGUANYLATE CYCLASE/PHOSPHODIESTERASE, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ggdef & eal domains, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, unknown function
• Biological source: THIOBACILLUS DENITRIFICANS
• Total number of polymer chains: 2
• Total formula weight: 67265.79

Authors

Chang, C.,Xu, X.,Cui, H.,Savchenko, A.,Edwards, A.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2010-05-20, release date: 2010-06-16, Last modification date: 2017-11-08)

• Primary citation: Tchigvintsev, A.,Xu, X.,Singer, A.,Chang, C.,Brown, G.,Proudfoot, M.,Cui, H.,Flick, R.,Anderson, W.F.,Joachimiak, A.,Galperin, M.Y.,Savchenko, A.,Yakunin, A.F.; Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.; J.Mol.Biol., 402:524-538, 2010; PubMed: 20691189; DOI: 10.1016/j.jmb.2010.07.050

Experimental method

X-RAY DIFFRACTION (2.35 Å)