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3FZZ

Structure of GrC

Summary for 3FZZ
Entry DOI10.2210/pdb3fzz/pdb
DescriptorGranzyme C, SULFATE ION (3 entities in total)
Functional Keywordshydrolase, cytolysis, protease, serine protease, zymogen
Biological sourceMus musculus (mouse)
Cellular locationCytoplasmic granule: P08882
Total number of polymer chains2
Total formula weight51056.51
Authors
Buckle, A.M.,Kaiserman, D.,Whisstock, J.C. (deposition date: 2009-01-27, release date: 2009-03-17, Last modification date: 2023-11-01)
Primary citationKaiserman, D.,Buckle, A.M.,Van Damme, P.,Irving, J.A.,Law, R.H.P.,Matthews, A.Y.,Bashtannyk-Puhalovich, T.,Langendorf, C.,Thompson, P.,Vandekerckhove, J.,Gevaert, K.,Whisstock, J.C.,Bird, P.I.
Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Proc.Natl.Acad.Sci.USA, 106:5587-5592, 2009
Cited by
PubMed: 19299505
DOI: 10.1073/pnas.0811968106
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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