3FZZ
Structure of GrC
Summary for 3FZZ
Entry DOI | 10.2210/pdb3fzz/pdb |
Descriptor | Granzyme C, SULFATE ION (3 entities in total) |
Functional Keywords | hydrolase, cytolysis, protease, serine protease, zymogen |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasmic granule: P08882 |
Total number of polymer chains | 2 |
Total formula weight | 51056.51 |
Authors | Buckle, A.M.,Kaiserman, D.,Whisstock, J.C. (deposition date: 2009-01-27, release date: 2009-03-17, Last modification date: 2023-11-01) |
Primary citation | Kaiserman, D.,Buckle, A.M.,Van Damme, P.,Irving, J.A.,Law, R.H.P.,Matthews, A.Y.,Bashtannyk-Puhalovich, T.,Langendorf, C.,Thompson, P.,Vandekerckhove, J.,Gevaert, K.,Whisstock, J.C.,Bird, P.I. Structure of granzyme C reveals an unusual mechanism of protease autoinhibition Proc.Natl.Acad.Sci.USA, 106:5587-5592, 2009 Cited by PubMed: 19299505DOI: 10.1073/pnas.0811968106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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