1XIQ
 
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2FHO
 | | NMR solution structure of the human spliceosomal protein complex p14-SF3b155 | | 分子名称: | spliceosomal protein SF3b155, spliceosomal protein p14 | | 著者 | Kuwasako, K, Dohmae, N, Inoue, M, Shirouzu, M, Guntert, P, Seraphin, B, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-26 | | 公開日 | 2006-12-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of the human spliceosomal protein complex p14-SF3b155
To be Published
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2C01
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2BZZ
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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1JIM
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4QXX
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8H6K
 | | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6E
 | | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-17 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6J
 | | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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8H6L
 | | Cryo-EM structure of human exon-defined spliceosome in the early B state. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | 登録日 | 2022-10-18 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
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7DCO
 | | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom | | 分子名称: | BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ... | | 著者 | Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. | | 登録日 | 2020-10-26 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
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8QKU
 | | SWR1-nucleosome complex in configuration 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Jalal, A.S.B, Wigley, D.B. | | 登録日 | 2023-09-18 | | 公開日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Nucleosome flipping drives kinetic proof reading and processivity of histone exchange by yeast SWR1 complex
To Be Published
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8QKV
 | | SWR1-nucleosome complex in configuration 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Jalal, A.S.B, Wigley, D.B. | | 登録日 | 2023-09-18 | | 公開日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Nucleosome flipping drives kinetic proof reading and processivity of histone exchange by yeast SWR1 complex
To Be Published
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7KBE
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7KBD
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2MA7
 | | Solution NMR Structure of Zinc finger protein Eos from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7992A | | 分子名称: | ZINC ION, Zinc finger protein Eos | | 著者 | Pulavarti, S.V, Mills, J.L, Wang, D, Jigabm, E, Hamilton, K, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2013-06-28 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure of Zinc finger protein Eos from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR7992A
To be Published
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1JLB
 | | CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 RT A-chain, HIV-1 RT B-chain | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
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1JLF
 | | CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 RT A-chain, HIV-1 RT B-chain | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-03 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
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2IC3
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3EEI
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A | | 分子名称: | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase | | 著者 | Ho, M, Rinaldo-matthis, A, Brown, R.L, Norris, G.E, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | | 登録日 | 2008-09-04 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A
To be Published
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1M73
 | | CRYSTAL STRUCTURE OF HUMAN PNP AT 2.3A RESOLUTION | | 分子名称: | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | 著者 | De Azevedo Jr, W.F, Marangoni Dos Santos, D, Canduri, F, Santos, G.C, Olivieri, J.R, Silva, R.G, Basso, L.A, Palma, M.S, Santos, D.S. | | 登録日 | 2002-07-18 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution.
Biochem.Biophys.Res.Commun., 308, 2003
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1V3Q
 | | Structure of human PNP complexed with DDI | | 分子名称: | 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Canduri, F, Pereira, J.H, dos Santos, D.M, Silva, R.G, Palma, M.S, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S. | | 登録日 | 2003-11-04 | | 公開日 | 2004-01-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of human purine nucleoside phosphorylase complexed with inosine and ddI
Biochem.Biophys.Res.Commun., 313, 2004
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4EVW
 | | Crystal Structure of the nucleoside-diphosphate-sugar pyrophosphorylase from Vibrio cholerae RC9. Northeast Structural Genomics Consortium (NESG) Target VcR193. | | 分子名称: | MAGNESIUM ION, Nucleoside-diphosphate-sugar pyrophosphorylase | | 著者 | Vorobiev, S, Neely, H, Su, M, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2012-04-26 | | 公開日 | 2012-05-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the nucleoside-diphosphate-sugar pyrophosphorylase from Vibrio cholerae RC9.
To be Published
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2HND
 | | Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with Nevirapine | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Ren, J, Nichols, C.E, Stamp, A, Chamberlain, P.P, Stammers, D.K. | | 登録日 | 2006-07-12 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
Febs J., 273, 2006
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2HNY
 | | Crystal Structure of E138K Mutant HIV-1 Reverse Transcriptase in Complex with Nevirapine | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Ren, J, Nichols, C.E, Stamp, A, Chamberlain, P.P, Stammers, D.K. | | 登録日 | 2006-07-13 | | 公開日 | 2006-09-05 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
Febs J., 273, 2006
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