7DCO

Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom

This is a non-PDB format compatible entry.

Summary for 7DCO

• Entry DOI: 10.2210/pdb7dco/pdb
• EMDB information: 30637
• Descriptor: PRP8 isoform 1, Sm protein F, Small nuclear ribonucleoprotein G, ... (53 entities in total)
• Functional Keywords: rna splicing, spliceosome, bact complex, prp2, spp2, atpase/helicase, activation, splicing
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 56
• Total formula weight: 2914319.90

Authors

Bai, R.,Wan, R.,Yan, C.,Qi, J.,Zhang, P.,Lei, J.,Shi, Y. (deposition date: 2020-10-26, release date: 2021-03-17, Last modification date: 2024-03-27)

• Primary citation: Bai, R.,Wan, R.,Yan, C.,Jia, Q.,Lei, J.,Shi, Y.; Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.; Science, 371:-, 2021; PubMed: 33243853; DOI: 10.1126/science.abe8863

Experimental method

ELECTRON MICROSCOPY (2.5 Å)