1V3Q

Structure of human PNP complexed with DDI

Summary for 1V3Q

Entry DOI	10.2210/pdb1v3q/pdb
Related	1M73 1PF7 1RCT 1V41 1V45
Descriptor	Purine nucleoside phosphorylase, SULFATE ION, 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, drug design, synchrotorn, ddi, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton (By similarity): P00491
Total number of polymer chains	1
Total formula weight	32578.10
Authors	Canduri, F.,Pereira, J.H.,dos Santos, D.M.,Silva, R.G.,Palma, M.S.,Basso, L.A.,de Azevedo Jr., W.F.,Santos, D.S. (deposition date: 2003-11-04, release date: 2004-01-20, Last modification date: 2023-10-25)
Primary citation	Canduri, F.,dos Santos, D.M.,Silva, R.G.,Mendes, M.A.,Basso, L.A.,Palma, M.S.,de Azevedo Jr., W.F.,Santos, D.S. Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Biochem.Biophys.Res.Commun., 313:907-914, 2004 Cited by PubMed: 14706628 DOI: 10.1016/j.bbrc.2003.11.179 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation