1PF7

CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH IMMUCILLIN H

Summary for 1PF7

Entry DOI	10.2210/pdb1pf7/pdb
Related	1M73
Descriptor	PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total)
Functional Keywords	purine nucleoside phosphorylase, drug design, synchrotron, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton (By similarity): P00491
Total number of polymer chains	1
Total formula weight	32739.32
Authors	De Azevedo Jr., W.F.,Canduri, F.,Dos Santos, D.M.,Pereira, J.H.,Dias, M.V.B.,Silva, R.G.,Mendes, M.A.,Palma, M.S.,Basso, L.A.,Santos, D.S. (deposition date: 2003-05-24, release date: 2004-06-01, Last modification date: 2023-09-20)
Primary citation	De Azevedo Jr., W.F.,Canduri, F.,Dos Santos, D.M.,Pereira, J.H.,Dias, M.V.B.,Silva, R.G.,Mendes, M.A.,Palma, M.S.,Basso, L.A.,Santos, D.S. Structural basis for inhibition of human PNP by immucillin-H Biochem.Biophys.Res.Commun., 309:917-922, 2003 Cited by PubMed: 13679061 DOI: 10.1016/j.bbrc.2003.08.094 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation