2OQ6
 
 | | Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys9 | | 分子名称: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-01-31 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
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2OQ7
 | | The crystal structure of JMJD2A complexed with Ni and N-oxalylglycine | | 分子名称: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-01-31 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
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4AAP
 | | Crystal structure of JMJD5 domain of human Lysine-specific demethylase 8 (KDM8) in complex with N-oxalylglycine (NOG) | | 分子名称: | LYSINE-SPECIFIC DEMETHYLASE 8, N-OXALYLGLYCINE, ZINC ION | | 著者 | Vollmar, M, Johansson, C, Krojer, T, Canning, P, Allerston, C, Gadhave, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U. | | 登録日 | 2011-12-05 | | 公開日 | 2012-02-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Jmjd5 Domain of Human Lysine- Specific Demethylase 8 (Kdm8) in Complex with N- Oxalylglycine (Nog)
To be Published
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6H8P
 | | JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Histone H1.4(18-32)K26me3 peptide (15-mer) | | 分子名称: | CHLORIDE ION, GLYCEROL, Histone H1.4, ... | | 著者 | Chowdhury, R, Walport, L.J, Schofield, C.J. | | 登録日 | 2018-08-03 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.983 Å) | | 主引用文献 | Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26.
FEBS Lett., 592, 2018
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6YW3
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4EZH
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6YW4
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4EYU
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4EZ4
 | | free KDM6B structure | | 分子名称: | Lysine-specific demethylase 6B, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Cheng, Z.J, Patel, D.J. | | 登録日 | 2012-05-02 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature, 488, 2012
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4GAZ
 | | Crystal Structure of a Jumonji Domain-containing Protein JMJD5 | | 分子名称: | Lysine-specific demethylase 8, N-OXALYLGLYCINE, NICKEL (II) ION | | 著者 | Wang, H, Zhou, X, Zhang, X, Tao, Y, Chen, N, Zang, J. | | 登録日 | 2012-07-26 | | 公開日 | 2013-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal Structure of a Jumonji Domain-containing Protein JMJD5
To be Published
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5LA9
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5L9R
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5FWE
 | | JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE | | 分子名称: | CHLORIDE ION, GLYCEROL, LYSINE-SPECIFIC DEMETHYLASE 4A, ... | | 著者 | Chowdhury, R, Walport, L.J, Schofield, C.J. | | 登録日 | 2016-02-15 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases.
Nat.Commun., 7, 2016
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4QKF
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4Y3O
 | | Crystal structure of Ribosomal oxygenase NO66 in complex with substrate Rpl8 peptide and Ni(II) and cofactor N-oxalyglycine | | 分子名称: | ACETATE ION, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, GLYCEROL, ... | | 著者 | Wang, C, Zhang, Q, Zang, J. | | 登録日 | 2015-02-10 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8.
Acta Crystallogr.,Sect.D, 71, 2015
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4IGQ
 | | Histone H3 Lysine 4 Demethylating Rice JMJ703 in complex with methylated H3K4 substrate | | 分子名称: | FE (III) ION, N-OXALYLGLYCINE, Os05g0196500 protein, ... | | 著者 | Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X. | | 登録日 | 2012-12-17 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
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4IDZ
 | | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-oxalylglycine (NOG) | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, N-OXALYLGLYCINE, ... | | 著者 | Aik, W.S, McDonough, M.A, Schofield, C.J. | | 登録日 | 2012-12-13 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Structural basis for inhibition of the fat mass and obesity associated protein (FTO)
J.Med.Chem., 56, 2013
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4JAA
 | | Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)LEU peptide | | 分子名称: | CONSENSUS ANKYRIN REPEAT DOMAIN-(d)LEU, Hypoxia-inducible factor 1-alpha inhibitor, N-OXALYLGLYCINE, ... | | 著者 | Scotti, J.S, Ge, W, McDonough, M.A, Schofield, C.J. | | 登録日 | 2013-02-18 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure of an oxygenase in complex with substrate
To be Published
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2OZN
 | | The Cohesin-Dockerin Complex of NagJ and NagH from Clostridium perfringens | | 分子名称: | CALCIUM ION, CHLORIDE ION, Hyalurononglucosaminidase, ... | | 著者 | Adams, J.J, Boraston, A, Smith, S.P. | | 登録日 | 2007-02-26 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of Clostridium perfringens toxin complex formation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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4NR1
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4NM6
 | | Crystal structure of TET2-DNA complex | | 分子名称: | 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', FE (II) ION, Methylcytosine dioxygenase TET2, ... | | 著者 | Hu, L, Li, Z, Cheng, J, Rao, Q, Gong, W, Liu, M, Wang, P, Xu, Y. | | 登録日 | 2013-11-14 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.026 Å) | | 主引用文献 | Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
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4NRP
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4LT5
 | | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA, MANGANESE (II) ION, ... | | 著者 | Hashimoto, H, Pais, J.E, Zhang, X, Saleh, L, Fu, Z.Q, Dai, N, Correa, I.R, Roberts, R.J, Zheng, Y, Cheng, X. | | 登録日 | 2013-07-23 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | | 主引用文献 | Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Nature, 506, 2014
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3LFM
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3KVB
 | | Structure of KIAA1718 Jumonji domain in complex with N-oxalylglycine | | 分子名称: | JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | | 登録日 | 2009-11-29 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
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