5FWE

JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE

Summary for 5FWE

Entry DOI	10.2210/pdb5fwe/pdb
Descriptor	LYSINE-SPECIFIC DEMETHYLASE 4A, SYNTHETIC PEPTIDE, NICKEL (II) ION, ... (8 entities in total)
Functional Keywords	jmjd2a, oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, double-stranded beta helix, dsbh, facial triad, demethylase, histone, jmjc domain, metal binding protein, epigenetic and transcription regulation, chromatin regulator, hydroxylation
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	4
Total formula weight	91992.96
Authors	Chowdhury, R.,Walport, L.J.,Schofield, C.J. (deposition date: 2016-02-15, release date: 2016-04-06, Last modification date: 2024-01-10)
Primary citation	Walport, L.J.,Hopkinson, R.J.,Chowdhury, R.,Schiller, R.,Ge, W.,Kawamura, A.,Schofield, C.J. Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases. Nat.Commun., 7:11974-, 2016 Cited by PubMed: 27337104 DOI: 10.1038/NCOMMS11974 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation