4NR1
Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)allyl-GLY peptide
Summary for 4NR1
Entry DOI | 10.2210/pdb4nr1/pdb |
Related | 4JAA |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)allyl glycine, ZINC ION, ... (6 entities in total) |
Functional Keywords | on-heme, dioxygenase, oxygenase, dna-binding, metal-binding, transcription, helix-loop-helix-beta, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9NWT6 |
Total number of polymer chains | 2 |
Total formula weight | 43326.78 |
Authors | Scotti, J.S.,McDonough, M.A.,Schofield, C.J. (deposition date: 2013-11-26, release date: 2015-01-21, Last modification date: 2023-12-06) |
Primary citation | Scotti, J.S. Structure of an oxygenase in complex with substrate To be Published, |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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