4NR1

Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)allyl-GLY peptide

Summary for 4NR1

• Entry DOI: 10.2210/pdb4nr1/pdb
• Related: 4JAA
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)allyl glycine, ZINC ION, ... (6 entities in total)
• Functional Keywords: on-heme, dioxygenase, oxygenase, dna-binding, metal-binding, transcription, helix-loop-helix-beta, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9NWT6
• Total number of polymer chains: 2
• Total formula weight: 43326.78

Authors

Scotti, J.S.,McDonough, M.A.,Schofield, C.J. (deposition date: 2013-11-26, release date: 2015-01-21, Last modification date: 2024-10-30)

• Primary citation: Scotti, J.S.; Structure of an oxygenase in complex with substrate; To be Published,

Experimental method

X-RAY DIFFRACTION (2.68 Å)