PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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3S44	Crystal Structure of Pasteurella multocida sialyltransferase M144D mutant with CMP bound 分子名称: Alpha-2,3/2,6-sialyltransferase/sialidase, CMP-3F(a)-Neu5Ac 著者 Sugiarto, G, Lau, K, Li, Y, Lim, S, Ames, J.B, Le, D.-T, Fisher, A.J, Chen, X. 登録日 2011-05-18 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewis(x). Acs Chem.Biol., 7, 2012
2H9R	Docking and dimerization domain (D/D) of the regulatory subunit of the Type II-alpha cAMP-dependent protein kinase A associated with a Peptide derived from an A-kinase anchoring protein (AKAP) 分子名称: 22-mer from A-kinase anchor protein 5, cAMP-dependent protein kinase type II-alpha regulatory subunit 著者 Newlon, M.G, Roy, M, Morikis, D, Hausken, Z.E, Coghlan, V, Scott, J.D, Jennings, P.A. 登録日 2006-06-10 公開日 2006-08-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. Embo J., 20, 2001
3AOC	Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket 分子名称: Acriflavine resistance protein B, ERYTHROMYCIN A 著者 Nakashima, R, Sakurai, K, Yamaguchi, A. 登録日 2010-09-23 公開日 2011-11-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket Nature, 480, 2011
1Z19	Crystal structure of a lambda integrase(75-356) dimer bound to a COC' core site 分子名称: 33-MER, 5'-D(*CP*TP*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*AP*TP*AP*CP*TP*AP*AP*GP*TP*TP*GP*GP*CP*AP*TP*TP*A)-3', ... 著者 Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. 登録日 2005-03-03 公開日 2005-06-28 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
2H5M	NMR Solution Structure of a GCN5-like putative N-acetyltransferase from Staphylococcus aureus complexed with acetyl-CoA. Northeast Structural Genomics Consortium Target ZR31 分子名称: ACETYL COENZYME *A, Acetyltransferase, GNAT family 著者 Cort, J.R, Ramelot, T.A, Acton, T.B, Ma, L, Xiao, R.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2006-05-26 公開日 2006-11-28 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins J.Struct.Funct.Genom., 9, 2008
2DRN	Docking and dimerization domain (D/D) of the Type II-alpha regulatory subunity of protein kinase A (PKA) in complex with a peptide from an A-kinase anchoring protein 分子名称: 24-residues peptide from an a-kinase anchoring protein, cAMP-dependent protein kinase type II-alpha regulatory subunit 著者 Newlon, M.G, Roy, M, Morikis, D, Hausken, Z.E, Coghlan, V, Scott, J.D, Jennings, P.A. 登録日 2006-06-11 公開日 2006-08-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. Embo J., 20, 2001
1UZW	ISOPENICILLIN N SYNTHASE WITH L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-ISODEHYDROVALINE 分子名称: D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-D-ISODEHYDROVALINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... 著者 Grummitt, A.R, Rutledge, P.J, Clifton, I.J, Baldwin, J.E. 登録日 2004-03-17 公開日 2004-06-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Active Site Mediated Elimination of Hydrogen Fluoride from a Fluorinated Substrate Analogue by Isopenicillin N Synthase Biochem.J., 382, 2004
1SQX	Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A 分子名称: Cytochrome b, Cytochrome c1, heme protein, ... 著者 Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. 登録日 2004-03-21 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
1J4J	Crystal Structure of Tabtoxin Resistance Protein (form II) complexed with an Acyl Coenzyme A 分子名称: ACETYL COENZYME *A, TABTOXIN RESISTANCE PROTEIN 著者 He, H, Ding, Y, Bartlam, M, Zhang, R, Duke, N, Joachimiak, A, Shao, Y, Cao, Z, Tang, H, Liu, Y, Jiang, F, Liu, J, Zhao, N, Rao, Z. 登録日 2001-10-02 公開日 2003-06-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation. J.Mol.Biol., 325, 2003
2NOV	Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target 分子名称: DNA topoisomerase 4 subunit A 著者 Laponogov, I, Veselkov, D.A, Sohi, M.K, Pan, X.S, Achari, A, Yang, C, Ferrara, J.D, Fisher, L.M, Sanderson, M.R. 登録日 2006-10-26 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target. PLoS ONE, 2, 2007
2NEO	SOLUTION NMR STRUCTURE OF A TWO-BASE DNA BULGE COMPLEXED WITH AN ENEDIYNE CLEAVING ANALOG, 11 STRUCTURES 分子名称: DNA (5'-D(*CP*CP*CP*GP*AP*TP*GP*CP*PGE*GP*CP*AP*AP*TP*TP*CP*GP*GP*G)-3'), SPIRO[[7-METHOXY-5-METHYL-1,2-DIHYDRO-NAPHTHALENE]-3,1'-[5-HYDROXY-9-[2-METHYLAMINO-2,6-DIDEOXYGALACTOPYRANOSYL-OXY]-5-(2-OXO-[1,3]DIOXOLAN-4-YL)-3A,5,9,9A-TETRAHYDRO-3H-1-OXA-CYCLOPENTA[A]-S-INDACEN-2-ONE]] 著者 Stassinopoulos, A, Ji, J, Gao, X, Goldberg, I.H. 登録日 1997-06-19 公開日 1998-01-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a two-base DNA bulge complexed with an enediyne cleaving analog. Science, 272, 1996
2BSW	Crystal structure of a glyphosate-N-acetyltransferase obtained by DNA shuffling. 分子名称: GLYCEROL, GLYPHOSATE N-ACETYLTRANSFERASE, OXIDIZED COENZYME A, ... 著者 Keenan, R.J, Siehl, D.L, Gorton, R, Castle, L.A. 登録日 2005-05-24 公開日 2005-06-08 最終更新日 2015-10-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 DNA Shuffling as a Tool for Protein Crystallization. Proc.Natl.Acad.Sci.USA, 102, 2005
2IL4	Crystal structure of At1g77540-Coenzyme A Complex 分子名称: COENZYME A, Protein At1g77540 著者 Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-10-02 公開日 2006-10-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.054 Å) 主引用文献 Structure of Arabidopsis thaliana At1g77540 Protein, a Minimal Acetyltransferase from the COG2388 Family. Biochemistry, 45, 2006
2CN0	Complex of Recombinant Human Thrombin with a Designed Inhibitor 分子名称: 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE, CALCIUM ION, HIRUDIN IIA, ... 著者 Hoffmann-Roder, A, Schweizer, E, Egger, J, Seiler, P, Obst-Sander, U, Wagner, B, Kansy, M, Banner, D.W, Diederich, F. 登録日 2006-05-17 公開日 2006-11-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups Into the P Pocket Chemmedchem, 1, 2006
2QPL	Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue 分子名称: 4-amino-7-methylpyrazolo[1,5-a][1,3,5]triazin-2(1H)-one, MAGNESIUM ION, Purine nucleoside phosphorylase, ... 著者 Pereira, H.M, Berdini, V, Cleasby, A, Garratt, R.C. 登録日 2007-07-24 公開日 2007-12-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue. Febs Lett., 581, 2007
2J62	Structure of a bacterial O-glcnacase in complex with glcnacstatin 分子名称: CHLORIDE ION, N-[(5R,6R,7R,8S)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDIN-8-YL]-2-METHYLPROPANAMIDE, O-GlcNAcase NagJ 著者 Dorfmueller, H.C, Borodkin, V.S, Schimpl, M, Shepherd, S.M, Shpiro, N.A, van Aalten, D.M.F. 登録日 2006-09-22 公開日 2007-02-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels. J. Am. Chem. Soc., 128, 2006
2BWH	Laue Structure of a Short Lived State of L29W Myoglobin 分子名称: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Schmidt, M, Nienhaus, K, Pahl, R, Krasselt, A, Anderson, S, Parak, F, Nienhaus, G.U, Srajer, V. 登録日 2005-07-14 公開日 2005-07-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand migration pathway and protein dynamics in myoglobin: a time-resolved crystallographic study on L29W MbCO. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
2I5W	Structure of hOGG1 crosslinked to DNA sampling a normal G adjacent to an oxoG 分子名称: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', 5'-D(P*CP*CP*AP*GP*(G42)P*TP*CP*TP*AP*C)-3', CALCIUM ION, ... 著者 Banerjee, A, Verdine, G.L. 登録日 2006-08-26 公開日 2006-10-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex. Proc.Natl.Acad.Sci.Usa, 103, 2006
2PVJ	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVL	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVK	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVN	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: Casein kinase II subunit alpha, N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVM	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVH	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: Casein kinase II subunit alpha, N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
1VHH	A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG 分子名称: SONIC HEDGEHOG, SULFATE ION, ZINC ION 著者 Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J. 登録日 1995-10-03 公開日 1996-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog. Nature, 378, 1995

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