3S44

Crystal Structure of Pasteurella multocida sialyltransferase M144D mutant with CMP bound

Summary for 3S44

Entry DOI	10.2210/pdb3s44/pdb
Related	2EX0 2EX1 2IHJ 2IHK 2IHZ 2ILV
Descriptor	Alpha-2,3/2,6-sialyltransferase/sialidase, CMP-3F(a)-Neu5Ac (3 entities in total)
Functional Keywords	gt-b fold, sialyltransferase, transferase
Biological source	Pasteurella multocida
Total number of polymer chains	1
Total formula weight	47039.79
Authors	Sugiarto, G.,Lau, K.,Li, Y.,Lim, S.,Ames, J.B.,Le, D.-T.,Fisher, A.J.,Chen, X. (deposition date: 2011-05-18, release date: 2012-08-15, Last modification date: 2023-09-13)
Primary citation	Sugiarto, G.,Lau, K.,Qu, J.,Li, Y.,Lim, S.,Mu, S.,Ames, J.B.,Fisher, A.J.,Chen, X. A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewis(x). Acs Chem.Biol., 7:1232-1240, 2012 Cited by PubMed: 22583967 DOI: 10.1021/cb300125k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation