2DRN

Docking and dimerization domain (D/D) of the Type II-alpha regulatory subunity of protein kinase A (PKA) in complex with a peptide from an A-kinase anchoring protein

Summary for 2DRN

• Entry DOI: 10.2210/pdb2drn/pdb
• Related: 1L6E 1R2A 2H9R 2HWN
• Descriptor: cAMP-dependent protein kinase type II-alpha regulatory subunit, 24-residues peptide from an a-kinase anchoring protein (2 entities in total)
• Functional Keywords: akap, pka, signal transduction, 4-helix bundle, helix-loop-helix, protein-peptide complex, transferase
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 3
• Total formula weight: 13330.19

Authors

Newlon, M.G.,Roy, M.,Morikis, D.,Hausken, Z.E.,Coghlan, V.,Scott, J.D.,Jennings, P.A. (deposition date: 2006-06-11, release date: 2006-08-29, Last modification date: 2024-05-29)

• Primary citation: Newlon, M.G.,Roy, M.,Morikis, D.,Carr, D.W.,Westphal, R.,Scott, J.D.,Jennings, P.A.; A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes.; Embo J., 20:1651-1662, 2001; PubMed: 11285229; DOI: 10.1093/emboj/20.7.1651

Experimental method

SOLUTION NMR