2NEO

SOLUTION NMR STRUCTURE OF A TWO-BASE DNA BULGE COMPLEXED WITH AN ENEDIYNE CLEAVING ANALOG, 11 STRUCTURES

Replaces:  1NEO

Summary for 2NEO

• Entry DOI: 10.2210/pdb2neo/pdb
• Descriptor: DNA (5'-D(*CP*CP*CP*GP*AP*TP*GP*CP*PGE*GP*CP*AP*AP*TP*TP*CP*GP*GP*G)-3'), SPIRO[[7-METHOXY-5-METHYL-1,2-DIHYDRO-NAPHTHALENE]-3,1'-[5-HYDROXY-9-[2-METHYLAMINO-2,6-DIDEOXYGALACTOPYRANOSYL-OXY]-5-(2-OXO-[1,3]DIOXOLAN-4-YL)-3A,5,9,9A-TETRAHYDRO-3H-1-OXA-CYCLOPENTA[A]-S-INDACEN-2-ONE]] (2 entities in total)
• Functional Keywords: dna, bulge dna, enediyne antibiotics antitumor agents, carbohydrates, bulge binding ligands, deoxyribonucleic acid
• Total number of polymer chains: 1
• Total formula weight: 6312.39

Authors

Stassinopoulos, A.,Ji, J.,Gao, X.,Goldberg, I.H. (deposition date: 1997-06-19, release date: 1998-01-28, Last modification date: 2022-03-16)

• Primary citation: Stassinopoulos, A.,Ji, J.,Gao, X.,Goldberg, I.H.; Solution structure of a two-base DNA bulge complexed with an enediyne cleaving analog.; Science, 272:1943-1946, 1996; PubMed: 8658168

Experimental method

SOLUTION NMR