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3AOC

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

Summary for 3AOC
Entry DOI10.2210/pdb3aoc/pdb
Related2DHH 2DR6 2DRD 3AOA 3AOB 3AOD
DescriptorAcriflavine resistance protein B, ERYTHROMYCIN A (3 entities in total)
Functional Keywordsmembrane protein, inner membrane, membrane protein-antibiotic complex, membrane protein/antibiotic
Biological sourceEscherichia coli
Cellular locationCell inner membrane ; Multi- pass membrane protein : P31224
Total number of polymer chains3
Total formula weight343387.15
Authors
Nakashima, R.,Sakurai, K.,Yamaguchi, A. (deposition date: 2010-09-23, release date: 2011-11-30, Last modification date: 2023-11-01)
Primary citationNakashima, R.,Sakurai, K.,Yamasaki, S.,Nishino, K.,Yamaguchi, A.
Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Nature, 480:565-569, 2011
Cited by
PubMed: 22121023
DOI: 10.1038/nature10641
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.34 Å)
Structure validation

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