2I5W
Structure of hOGG1 crosslinked to DNA sampling a normal G adjacent to an oxoG
Summary for 2I5W
Entry DOI | 10.2210/pdb2i5w/pdb |
Related | 1EBM 1KO9 1YQK |
Descriptor | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', 5'-D(P*CP*CP*AP*GP*(G42)P*TP*CP*TP*AP*C)-3', N-glycosylase/DNA lyase, ... (6 entities in total) |
Functional Keywords | disulfide crosslink, protein-dna complex, dna glycosylase, hydrolase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus, nucleoplasm . Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 42362.82 |
Authors | Banerjee, A.,Verdine, G.L. (deposition date: 2006-08-26, release date: 2006-10-17, Last modification date: 2024-02-21) |
Primary citation | Banerjee, A.,Verdine, G.L. A nucleobase lesion remodels the interaction of its normal neighbor in a DNA glycosylase complex. Proc.Natl.Acad.Sci.Usa, 103:15020-15025, 2006 Cited by PubMed: 17015827DOI: 10.1073/pnas.0603644103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report