2I5W
Structure of hOGG1 crosslinked to DNA sampling a normal G adjacent to an oxoG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3' | polymer | 12 | 3727.4 | 1 | |||
| 2 | B (F) | 5'-D(P*CP*CP*AP*GP*(G42)P*TP*CP*TP*AP*C)-3' | polymer | 10 | 3021.0 | 1 | |||
| 3 | C (A) | N-glycosylase/DNA lyase | polymer | 315 | 35442.1 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) | Homo sapiens (human) | |
| 4 | D, E (F, A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G, H, I (E, F, A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 12 - 323 (UniProt: O15527)
| PDB | External Database | Details |
|---|---|---|
| Ser 9 | - | cloning artifact |
| Glu 10 | - | cloning artifact |
| Phe 11 | - | cloning artifact |
| Cys 149 | Asn 149 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 42190.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 172.3 | |
| All* | Total formula weight | 42362.8 |
