1KO9
Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1
Summary for 1KO9
Entry DOI | 10.2210/pdb1ko9/pdb |
Related | 1EBM 1FN7 |
Descriptor | 8-oxoguanine DNA glycosylase, SULFATE ION (3 entities in total) |
Functional Keywords | helix-hairpin-helix dna-glycosylase, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 1 |
Total formula weight | 39026.29 |
Authors | Bjoras, M.,Seeberg, E.,Luna, L.,Pearl, L.H.,Barrett, T.E. (deposition date: 2001-12-20, release date: 2002-01-09, Last modification date: 2023-08-16) |
Primary citation | Bjoras, M.,Seeberg, E.,Luna, L.,Pearl, L.H.,Barrett, T.E. Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. J.Mol.Biol., 317:171-177, 2002 Cited by PubMed: 11902834DOI: 10.1006/jmbi.2002.5400 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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