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1KO9

Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1

Summary for 1KO9
Entry DOI10.2210/pdb1ko9/pdb
Related1EBM 1FN7
Descriptor8-oxoguanine DNA glycosylase, SULFATE ION (3 entities in total)
Functional Keywordshelix-hairpin-helix dna-glycosylase, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
Total number of polymer chains1
Total formula weight39026.29
Authors
Bjoras, M.,Seeberg, E.,Luna, L.,Pearl, L.H.,Barrett, T.E. (deposition date: 2001-12-20, release date: 2002-01-09, Last modification date: 2023-08-16)
Primary citationBjoras, M.,Seeberg, E.,Luna, L.,Pearl, L.H.,Barrett, T.E.
Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase.
J.Mol.Biol., 317:171-177, 2002
Cited by
PubMed: 11902834
DOI: 10.1006/jmbi.2002.5400
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

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