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8R1N
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BU of 8r1n by Molmil
Pim1 in complex with 4-(4-hydroxyphenethyl)benzoic acid and Pimtide
分子名称: 4-(4-hydroxyphenethyl)benzoic acid, Pimtide, Serine/threonine-protein kinase pim-1
著者Hochban, P.M.M, Heine, A, Diederich, W.E.
登録日2023-11-02
公開日2024-03-20
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors.
Arch Pharm, 357, 2024
8R1P
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BU of 8r1p by Molmil
Pim1 in complex with 6-bromobenzo[d]oxazol-2-amine and Pimtide
分子名称: 4-(4-aminostyryl)benzoic acid, Pimtide, Serine/threonine-protein kinase pim-1
著者Hochban, P.M.M, Heine, A, Diederich, W.E.
登録日2023-11-02
公開日2024-03-20
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors.
Arch Pharm, 357, 2024
8UUE
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BU of 8uue by Molmil
Glycine-bound GluN1a-3A LBD heterotetramer (local refinement)
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 3A
著者Michalski, K, Furukawa, H.
登録日2023-11-01
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel.
Sci Adv, 10, 2024
8WZ2
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BU of 8wz2 by Molmil
Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex
分子名称: G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y.
登録日2023-11-01
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor.
Cell Discov, 10, 2024
8R18
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BU of 8r18 by Molmil
Pim1 in complex with (E)-4-(4-hydroxystyryl)benzoic acid and Pimtide
分子名称: (E)-4-(4-hydroxystyryl)benzoic acid, 1,2-ETHANEDIOL, GLYCEROL, ...
著者Hochban, P.M.M, Heine, A, Diederich, W.E.
登録日2023-11-01
公開日2024-03-20
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors.
Arch Pharm, 357, 2024
8R10
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BU of 8r10 by Molmil
Pim1 in complex with 4-(4-hydroxystyryl)benzoic acid and Pimtide
分子名称: (Z)-4-(4-hydroxystyryl)benzoic acid, Pimtide, Serine/threonine-protein kinase pim-1
著者Hochban, P.M.M, Heine, A, Diederich, W.E.
登録日2023-11-01
公開日2024-03-20
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors.
Arch Pharm, 357, 2024
8UTP
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BU of 8utp by Molmil
KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTL
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BU of 8utl by Molmil
Bovine trypsin in complex with Thr3Dap mutated microviridin J
分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
著者Chen, W, Bruner, S.D.
登録日2023-10-31
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Alternative Linkage Chemistries in the Chemoenzymatic Synthesis of Microviridin-Based Cyclic Peptides.
Org.Lett., 26, 2024
8UTV
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BU of 8utv by Molmil
KIF1A[1-393] P305L mutant ADP bound in complex with a microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTN
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BU of 8utn by Molmil
KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule (class T23L1)
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTY
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BU of 8uty by Molmil
KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTQ
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BU of 8utq by Molmil
KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02*
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTU
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BU of 8utu by Molmil
KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTT
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BU of 8utt by Molmil
KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTO
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BU of 8uto by Molmil
KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule - class T2L1
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTR
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BU of 8utr by Molmil
KIF1A[1-393] ADP bound in complex with a microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTW
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BU of 8utw by Molmil
KIF1A[1-393] P305L mutant APO in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8UTS
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BU of 8uts by Molmil
KIF1A[1-393] APO in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ...
著者Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H.
登録日2023-10-31
公開日2024-06-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L
To Be Published
8R09
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BU of 8r09 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0A
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BU of 8r0a by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R08
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BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0B
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BU of 8r0b by Molmil
Cryo-EM structure of the cross-exon pre-B+ATP complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
著者Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
登録日2023-10-31
公開日2024-05-22
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0E
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BU of 8r0e by Molmil
p97 (VCP) mutant - F266A
分子名称: Transitional endoplasmic reticulum ATPase
著者Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A.
登録日2023-10-31
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献p97 (VCP) mutant - F266A
To Be Published
8USX
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BU of 8usx by Molmil
Glycine-bound GluN1a-3A NMDA receptor
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 3A
著者Michalski, K, Furukawa, H.
登録日2023-10-30
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel.
Sci Adv, 10, 2024
8QZZ
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BU of 8qzz by Molmil
Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Yan, Y, Ron, D.
登録日2023-10-30
公開日2024-03-20
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-07-17に公開中

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