8R1N
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8R1P
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8UUE
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8WZ2
| Structure of 26RFa-pyroglutamylated RFamide peptide receptor complex | 分子名称: | G-alpha q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Jin, S, Li, X, Xu, Y, Guo, S, Wu, C, Zhang, H, Yuan, Q, Xu, H.E, Xie, X, Jiang, Y. | 登録日 | 2023-11-01 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor. Cell Discov, 10, 2024
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8R18
| Pim1 in complex with (E)-4-(4-hydroxystyryl)benzoic acid and Pimtide | 分子名称: | (E)-4-(4-hydroxystyryl)benzoic acid, 1,2-ETHANEDIOL, GLYCEROL, ... | 著者 | Hochban, P.M.M, Heine, A, Diederich, W.E. | 登録日 | 2023-11-01 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | What doesn't fit is made to fit: Pim-1 kinase adapts to the configuration of stilbene-based inhibitors. Arch Pharm, 357, 2024
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8R10
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8UTP
| KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTL
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8UTV
| KIF1A[1-393] P305L mutant ADP bound in complex with a microtubule | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTN
| KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule (class T23L1) | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTY
| KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTQ
| KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02* | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTU
| KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTT
| KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTO
| KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule - class T2L1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTR
| KIF1A[1-393] ADP bound in complex with a microtubule | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTW
| KIF1A[1-393] P305L mutant APO in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8UTS
| KIF1A[1-393] APO in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | 著者 | Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. | 登録日 | 2023-10-31 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
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8R09
| Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-31 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R0A
| Cryo-EM structure of the cross-exon pre-B+5'ss complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-31 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R08
| Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-31 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R0B
| Cryo-EM structure of the cross-exon pre-B+ATP complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-31 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R0E
| p97 (VCP) mutant - F266A | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A. | 登録日 | 2023-10-31 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | p97 (VCP) mutant - F266A To Be Published
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8USX
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8QZZ
| Crystal structure of human eIF2 alpha-gamma complexed with PPP1R15A_420-452 | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Yan, Y, Ron, D. | 登録日 | 2023-10-30 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Substrate recruitment via eIF2 gamma enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response. Proc.Natl.Acad.Sci.USA, 121, 2024
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