8UTY
KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule
Summary for 8UTY
Entry DOI | 10.2210/pdb8uty/pdb |
EMDB information | 42553 |
Descriptor | Tubulin alpha-1B chain, Tubulin beta-2B chain, Kinesin-like protein KIF1A, ... (8 entities in total) |
Functional Keywords | kif1a, kinesin, motility, microtubule, tubulin, motor protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 354495.43 |
Authors | Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. (deposition date: 2023-10-31, release date: 2024-06-12) |
Primary citation | Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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