8UTT

KIF1A[1-393] P305L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule

Summary for 8UTT

• Entry DOI: 10.2210/pdb8utt/pdb
• EMDB information: 42549
• Descriptor: Kinesin-like protein KIF1A, Tubulin alpha-1B chain, Tubulin beta-2B chain, ... (8 entities in total)
• Functional Keywords: kif1a, kinesin, motility, microtubule, tubulin, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 354495.43

Authors

Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. (deposition date: 2023-10-31, release date: 2024-06-12)

• Primary citation: Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H.; Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)