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1KAT
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BU of 1kat by Molmil
Solution Structure of a Phage-Derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor
分子名称: Phage-Derived Peptide Antagonist, Vascular Endothelial Growth Factor
著者Pan, B, Li, B, Russell, S.J, Tom, J.Y.K, Cochran, A.G, Fairbrother, W.J.
登録日2001-11-02
公開日2002-11-02
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution Structure of a Phage-derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor
J.Mol.Biol., 316, 2002
2FJG
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BU of 2fjg by Molmil
Structure of the G6 Fab, a phage derived Fab fragment, in complex with VEGF
分子名称: Fab heavy chain, Fab light chain, SULFATE ION, ...
著者Wiesmann, C.
登録日2006-01-02
公開日2006-02-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.
J.Biol.Chem., 281, 2006
1MKG
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BU of 1mkg by Molmil
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)
分子名称: Vascular Endothelial Growth Factor A
著者Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
登録日2002-08-29
公開日2002-12-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
5HHC
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BU of 5hhc by Molmil
Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n
分子名称: D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A
著者Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S.
登録日2016-01-10
公開日2016-03-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11, 2016
5FV1
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BU of 5fv1 by Molmil
Crystal structure of hVEGF in complex with VK domain antibody
分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR A, VK DOMAIN ANTIBODY
著者Chung, C, Walker, A.
登録日2016-02-02
公開日2016-02-17
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept.
J.Biol.Chem., 291, 2016
5HHD
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BU of 5hhd by Molmil
Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21
分子名称: D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ...
著者Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S.
登録日2016-01-10
公開日2016-03-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11, 2016
1MJV
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BU of 1mjv by Molmil
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A)
分子名称: Vascular Endothelial Growth Factor A
著者Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
登録日2002-08-28
公開日2002-12-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1MKK
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BU of 1mkk by Molmil
Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)
分子名称: Vascular Endothelial Growth Factor A
著者Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
登録日2002-08-29
公開日2002-12-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
3QTK
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BU of 3qtk by Molmil
The crystal structure of chemically synthesized VEGF-A
分子名称: ACETATE ION, GLYCEROL, Vascular endothelial growth factor A, ...
著者Mandal, K, Kent, S.B.H.
登録日2011-02-22
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Total chemical synthesis of biologically active vascular endothelial growth factor.
Angew.Chem.Int.Ed.Engl., 50, 2011
2GNN
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BU of 2gnn by Molmil
Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ...
著者Prota, A.E, Pieren, M, Wagner, A, Kostrewa, D, Winkler, F.K, Ballmer-Hofer, K.
登録日2006-04-10
公開日2006-05-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity.
J.Biol.Chem., 281, 2006
1TZI
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BU of 1tzi by Molmil
Crystal Structure of the Fab YADS2 Complexed with h-VEGF
分子名称: Fab YADS2 Heavy Chain, Fab YADS2 Light Chain, Vascular endothelial growth factor A
著者Fellouse, F.A, Wiesmann, C, Sidhu, S.S.
登録日2004-07-10
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
Proc.Natl.Acad.Sci.USA, 101, 2004
7KEZ
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BU of 7kez by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 16_0325) in complex with VEGF
分子名称: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
著者Shi, R, Manenda, M.S, Picard, M.-E.
登録日2020-10-13
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF1
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BU of 7kf1 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 14_0130) in complex with VEGF
分子名称: CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, anti-VEGF-A Fab bH1 heavy chain, ...
著者Shi, R, Picard, M.-E, Manenda, M.S.
登録日2020-10-13
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7KF0
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BU of 7kf0 by Molmil
Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform L-VEGF206 of Vascular endothelial growth factor A, ...
著者Shi, R, Picard, M.-E.
登録日2020-10-13
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF
to be published
7LL8
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BU of 7ll8 by Molmil
D-Protein RFX-V1 Bound to the VEGFR1 Domain 2 Site on VEGF-A
分子名称: Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V1
著者Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S.
登録日2021-02-03
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth.
Acs Chem.Biol., 16, 2021
7LL9
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BU of 7ll9 by Molmil
D-Protein RFX-V2 Bound to the VEGFR1 Domain 3 Site on VEGF-A
分子名称: Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V2
著者Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S.
登録日2021-02-03
公開日2021-03-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth.
Acs Chem.Biol., 16, 2021
6Z13
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BU of 6z13 by Molmil
VEGF-A 13:107 crystallized with 3C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, AMINO GROUP, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-05-12
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
6Z3F
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BU of 6z3f by Molmil
VEGF-A 13:107 crystallized with 2C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, AMINO GROUP, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-05-20
公開日2021-06-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
6ZBR
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BU of 6zbr by Molmil
VEGF-A 13:107 crystallized with 4C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Chains: P, PHOSPHATE ION, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-06-09
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
6ZCD
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BU of 6zcd by Molmil
VEGF-A 13:107 crystallized with 1C bicyclic peptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Derived from V114 peptide, PHOSPHATE ION, ...
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-06-10
公開日2021-06-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
6ZFL
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BU of 6zfl by Molmil
High resolution structure of VEGF-A 12:107 crystallized in tetragonal form
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Vascular endothelial growth factor A
著者Gaucher, J.-F, Broussy, S, Reille-Seroussi, M.
登録日2020-06-17
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
1VPF
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BU of 1vpf by Molmil
STRUCTURE OF HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR
分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR
著者Muller, Y.A, De Vos, A.M.
登録日1997-04-08
公開日1998-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site.
Proc.Natl.Acad.Sci.USA, 94, 1997
1VPP
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BU of 1vpp by Molmil
COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE
分子名称: PROTEIN (PEPTIDE V108), PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR)
著者Wiesmann, C, Christinger, H.W, Cochran, A.G, Cunningham, B.C, Fairbrother, W.J, Keenan, C.J, Meng, G, de Vos, A.M.
登録日1998-10-09
公開日1999-02-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the complex between VEGF and a receptor-blocking peptide.
Biochemistry, 37, 1998
1TZH
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BU of 1tzh by Molmil
Crystal Structure of the Fab YADS1 Complexed with h-VEGF
分子名称: Fab YADS1 Heavy Chain, Fab YADS1 Light Chain, Vascular endothelial growth factor A
著者Fellouse, F.A, Wiesmann, C, Sidhu, S.S.
登録日2004-07-09
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
Proc.Natl.Acad.Sci.USA, 101, 2004
1WQ8
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BU of 1wq8 by Molmil
Crystal structure of Vammin, a VEGF-F from a snake venom
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Vascular endothelial growth factor toxin
著者Suto, K, Yamazaki, Y, Morita, T, Mizuno, H.
登録日2004-09-23
公開日2004-12-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1.
J.Biol.Chem., 280, 2005

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