6ZCD

VEGF-A 13:107 crystallized with 1C bicyclic peptide

Summary for 6ZCD

• Entry DOI: 10.2210/pdb6zcd/pdb
• Related: 6Z13 6Z3F 6ZBR
• Descriptor: Derived from V114 peptide, Vascular endothelial growth factor A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: growth factor, peptide ligand, lactam bridge, alpha-helix stabilization, signaling protein, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 24881.74

Authors

Gaucher, J.-F.,Broussy, S.,Reille-Seroussi, M. (deposition date: 2020-06-10, release date: 2021-06-23, Last modification date: 2024-01-24)

• Primary citation: Gaucher, J.F.,Reille-Seroussi, M.,Broussy, S.; Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.; Chemistry, 2022; PubMed: 35665969; DOI: 10.1002/chem.202200465

Experimental method

X-RAY DIFFRACTION (1.8 Å)