6Z3F
VEGF-A 13:107 crystallized with 2C bicyclic peptide
Summary for 6Z3F
Entry DOI | 10.2210/pdb6z3f/pdb |
Descriptor | Chains: P, Vascular endothelial growth factor A, AMINO GROUP, ... (6 entities in total) |
Functional Keywords | growth factor, peptide ligand, lactam bridge, alpha-helix stabilization, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 24628.36 |
Authors | Gaucher, J.-F.,Broussy, S.,Reille-Seroussi, M. (deposition date: 2020-05-20, release date: 2021-06-02, Last modification date: 2024-05-01) |
Primary citation | Gaucher, J.F.,Reille-Seroussi, M.,Broussy, S. Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands. Chemistry, 2022 Cited by PubMed: 35665969DOI: 10.1002/chem.202200465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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