Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5HHC

Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n

Summary for 5HHC
Entry DOI10.2210/pdb5hhc/pdb
Related4GLN
DescriptorVascular endothelial growth factor A, D- Vascular endothelial growth factor-A, GLYCEROL, ... (4 entities in total)
Functional Keywordsheterochiral protein-protein complex, d-protein antagonist, growth factor-inhibitor complex, racemic protein crystallography, de novo protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight39696.48
Authors
Uppalapati, M.,Lee, D.J.,Mandal, K.,Kent, S.B.H.,Sidhu, S. (deposition date: 2016-01-10, release date: 2016-03-09, Last modification date: 2023-11-15)
Primary citationUppalapati, M.,Lee, D.J.,Mandal, K.,Li, H.,Miranda, L.P.,Lowitz, J.,Kenney, J.,Adams, J.J.,Ault-Riche, D.,Kent, S.B.,Sidhu, S.S.
A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11:1058-1065, 2016
Cited by
PubMed: 26745345
DOI: 10.1021/acschembio.5b01006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon