6ZFL
High resolution structure of VEGF-A 12:107 crystallized in tetragonal form
Summary for 6ZFL
Entry DOI | 10.2210/pdb6zfl/pdb |
Related | 6Z13 6Z3F 6ZBR 6ZCD |
Descriptor | Vascular endothelial growth factor A, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | growth factor, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 23277.67 |
Authors | Gaucher, J.-F.,Broussy, S.,Reille-Seroussi, M. (deposition date: 2020-06-17, release date: 2021-06-30, Last modification date: 2024-01-24) |
Primary citation | Gaucher, J.F.,Reille-Seroussi, M.,Broussy, S. Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands. Chemistry, 2022 Cited by PubMed: 35665969DOI: 10.1002/chem.202200465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)