3QTK
The crystal structure of chemically synthesized VEGF-A
Summary for 3QTK
| Entry DOI | 10.2210/pdb3qtk/pdb |
| Descriptor | Vascular endothelial growth factor A, ACETATE ION, trifluoroacetic acid, ... (5 entities in total) |
| Functional Keywords | covalent dimer, cysteine knot protein, growth factor, x-ray crystal structure, human vegf-a, hormone |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: P15692 |
| Total number of polymer chains | 6 |
| Total formula weight | 73216.95 |
| Authors | Mandal, K.,Kent, S.B.H. (deposition date: 2011-02-22, release date: 2011-07-27, Last modification date: 2023-09-13) |
| Primary citation | Mandal, K.,Kent, S.B. Total chemical synthesis of biologically active vascular endothelial growth factor. Angew.Chem.Int.Ed.Engl., 50:8029-8033, 2011 Cited by PubMed: 21744452DOI: 10.1002/anie.201103237 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.849 Å) |
Structure validation
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