6ZBR
VEGF-A 13:107 crystallized with 4C bicyclic peptide
Summary for 6ZBR
Entry DOI | 10.2210/pdb6zbr/pdb |
Related | 6Z13 6Z3F |
Descriptor | Chains: P, Vascular endothelial growth factor A, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | growth factor, peptide ligand, lactam bridge, alpha-helix stabilization, signaling protein, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 24895.76 |
Authors | Gaucher, J.-F.,Broussy, S.,Reille-Seroussi, M. (deposition date: 2020-06-09, release date: 2021-06-23, Last modification date: 2024-01-24) |
Primary citation | Gaucher, J.F.,Reille-Seroussi, M.,Broussy, S. Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands. Chemistry, 2022 Cited by PubMed: 35665969DOI: 10.1002/chem.202200465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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