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7YPR
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Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1.
分子名称: COPPER (II) ION, POTASSIUM ION, Superoxide dismutase [Cu-Zn], ...
著者Sim, K.-S, Fukuda, Y, Inoue, T.
登録日2022-08-04
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1.
Acta Crystallogr.,Sect.F, 79, 2023
7B4O
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A Bacteroidetes bacterium CuZn-superoxide dismutase with ZnZn metalation
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Wright, G.S.A.
登録日2020-12-02
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Bacterial Evolutionary Precursors of Eukaryotic Copper-Zinc Superoxide Dismutases.
Mol.Biol.Evol., 38, 2021
7B4P
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A Bacteroidetes bacterium CuZn-superoxide dismutase with CuZn metalation
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Wright, G.S.A.
登録日2020-12-02
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Bacterial Evolutionary Precursors of Eukaryotic Copper-Zinc Superoxide Dismutases.
Mol.Biol.Evol., 38, 2021
5YTU
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BU of 5ytu by Molmil
Structure of human SOD1 complexed with isoproteranol in C2221 space group
分子名称: Dihydrogen tetrasulfide, GLYCEROL, ISOPRENALINE, ...
著者Manjula, R, Padmanabhan, B.
登録日2017-11-20
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018
8IQ0
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BU of 8iq0 by Molmil
Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ...
著者Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C.
登録日2023-03-15
公開日2023-09-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
8IQ1
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BU of 8iq1 by Molmil
Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ...
著者Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C.
登録日2023-03-15
公開日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
7XX3
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Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)
分子名称: (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Padmanabhan, B, Unni, S.
登録日2022-05-28
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
5YTO
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BU of 5yto by Molmil
Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound.
分子名称: 4-[(1~{R})-2-(naphthalen-2-ylmethylamino)-1-oxidanyl-ethyl]benzene-1,2-diol, GLYCEROL, PENTASULFIDE-SULFUR, ...
著者Padmanabhan, B, Manjula, R.
登録日2017-11-19
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018
5YUL
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BU of 5yul by Molmil
Native Structure of hSOD1 in P6322 space group
分子名称: Dihydrogen tetrasulfide, GLYCEROL, Superoxide dismutase [Cu-Zn], ...
著者Manjula, R, Padmanabhan, B.
登録日2017-11-22
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018
8JD8
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BU of 8jd8 by Molmil
Crystal structure of Citrus limon Cu-Zn superoxide dismutase
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T.
登録日2023-05-12
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon.
Acta Crystallogr.,Sect.F, 79, 2023
6Z4G
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BU of 6z4g by Molmil
A4V mutant of human SOD1 bound with ebselen in P21 space group
分子名称: ACETATE ION, CHLORIDE ION, N-phenyl-2-selanylbenzamide, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4I
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A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 3 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z3V
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BU of 6z3v by Molmil
A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group
分子名称: 5-fluoranyl-~{N}-(3-morpholin-4-ylcarbonylphenyl)-2-selanyl-benzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-22
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
6Z4O
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BU of 6z4o by Molmil
A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 1 in P21 space group
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
7CJV
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BU of 7cjv by Molmil
Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment
分子名称: Monomeric Human Cu,Zn Superoxide dismutase
著者Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K.
登録日2020-07-14
公開日2021-05-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel.
J.Phys.Chem.B, 125, 2021
4BCZ
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BU of 4bcz by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form.
分子名称: SUPEROXIDE DISMUTASE [CU-ZN]
著者Saraboji, K, Awad, W, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T.
登録日2012-10-03
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
4B3E
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BU of 4b3e by Molmil
Structure of copper-zinc superoxide dismutase complexed with bicarbonate.
分子名称: CARBONATE ION, COPPER (II) ION, SULFATE ION, ...
著者Strange, R.W, Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2012-07-23
公開日2012-09-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase.
Plos One, 7, 2012
4BD4
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BU of 4bd4 by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F
分子名称: GLYCEROL, SUPEROXIDE DISMUTASE [CU-ZN]
著者Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T.
登録日2012-10-04
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
2JLP
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BU of 2jlp by Molmil
Crystal structure of human extracellular copper-zinc superoxide dismutase.
分子名称: COPPER (II) ION, EXTRACELLULAR SUPEROXIDE DISMUTASE (CU-ZN), THIOCYANATE ION, ...
著者Antonyuk, S.V, Strange, R.W, Marklund, S.L, Hasnain, S.S.
登録日2008-09-14
公開日2009-03-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding.
J.Mol.Biol., 388, 2009
4BCY
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BU of 4bcy by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F
分子名称: CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ...
著者Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T.
登録日2012-10-03
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.272 Å)
主引用文献Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
7CJW
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BU of 7cjw by Molmil
Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment
分子名称: Monomeric Human Cu,Zn Superoxide dismutase
著者Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K.
登録日2020-07-14
公開日2021-05-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel.
J.Phys.Chem.B, 125, 2021
7T8F
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BU of 7t8f by Molmil
G93A mutant of human SOD1 bound with Ebselen in P21 space group
分子名称: ACETATE ION, N-phenyl-2-selanylbenzamide, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024
7T8E
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BU of 7t8e by Molmil
G93A mutant of human SOD1 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024
7T8H
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BU of 7t8h by Molmil
G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024
7T8G
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BU of 7t8g by Molmil
G93A mutant of human SOD1 bound with MR6-8-2 in P21 space group
分子名称: ACETATE ION, SELENIUM ATOM, SULFATE ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024

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