1WR6
| Crystal structure of GGA3 GAT domain in complex with ubiquitin | 分子名称: | ADP-ribosylation factor binding protein GGA3, ubiquitin | 著者 | Kawasaki, M, Shiba, T, Shiba, Y, Yamaguchi, Y, Matsugaki, N, Igarashi, N, Suzuki, M, Kato, R, Kato, K, Nakayama, K, Wakatsuki, S. | 登録日 | 2004-10-12 | 公開日 | 2005-06-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular mechanism of ubiquitin recognition by GGA3 GAT domain. Genes Cells, 10, 2005
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4BOZ
| Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin | 分子名称: | GLYCEROL, UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C | 著者 | Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. | 登録日 | 2013-05-22 | 公開日 | 2013-07-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
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1WRD
| Crystal structure of Tom1 GAT domain in complex with ubiquitin | 分子名称: | Target of Myb protein 1, Ubiquitin | 著者 | Akutsu, M, Kawasaki, M, Katoh, Y, Shiba, T, Yamaguchi, Y, Kato, R, Kato, K, Nakayama, K, Wakatsuki, S. | 登録日 | 2004-10-14 | 公開日 | 2005-10-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain. Febs Lett., 579, 2005
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1XD3
| Crystal structure of UCHL3-UbVME complex | 分子名称: | MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ... | 著者 | Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R. | 登録日 | 2004-09-03 | 公開日 | 2004-11-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate J.Biol.Chem., 280, 2005
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1XT9
| Crystal Structure of Den1 in complex with Nedd8 | 分子名称: | Neddylin, Sentrin-specific protease 8 | 著者 | Reverter, D, Wu, K, Erdene, T.G, Pan, Z.Q, Wilkinson, K.D, Lima, C.D. | 登録日 | 2004-10-21 | 公開日 | 2004-12-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1. J.Mol.Biol., 345, 2005
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4B9K
| pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound | 分子名称: | (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | 著者 | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | 登録日 | 2012-09-05 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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4BKT
| von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide | 分子名称: | (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ... | 著者 | Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. | 登録日 | 2013-04-29 | 公開日 | 2013-11-27 | 最終更新日 | 2017-07-12 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
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4BKS
| von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide | 分子名称: | (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | 著者 | Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. | 登録日 | 2013-04-29 | 公開日 | 2013-11-27 | 最終更新日 | 2014-01-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
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1YX6
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1YX5
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2BKR
| NEDD8 NEDP1 complex | 分子名称: | NEDDYLIN, SENTRIN-SPECIFIC PROTEASE 8 | 著者 | Shen, L.N, Liu, H, Dong, C, Xirodimas, D, Naismith, J.H, Hay, R.T. | 登録日 | 2005-02-18 | 公開日 | 2005-09-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of Nedd8 Ubiquitin Discrimination by the Deneddylating Enzyme Nedp1 Embo J., 24, 2005
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4ASW
| Structure of the complex between the N-terminal dimerisation domain of Sgt2 and the UBL domain of Get5 | 分子名称: | SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, UBIQUITIN-LIKE PROTEIN MDY2 | 著者 | Simon, A.C, Simpson, P.J, Goldstone, R.M, Krysztofinska, E.M, Murray, J.W, High, S, Isaacson, R.L. | 登録日 | 2012-05-03 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Sgt2/Get5 Complex Provides Insights Into Get-Mediated Targeting of Tail-Anchored Membrane Proteins Proc.Natl.Acad.Sci.USA, 110, 2013
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4B95
| pVHL-EloB-EloB-EloC complex_(2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound | 分子名称: | (2S,4R)-1-(2-chlorophenyl)carbonyl-N-[(4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | 著者 | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | 登録日 | 2012-08-31 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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2C7M
| Human Rabex-5 residues 1-74 in complex with Ubiquitin | 分子名称: | RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, UBIQUITIN, ZINC ION | 著者 | Penengo, L, Mapelli, M, Murachelli, A.G, Confalioneri, S, Magri, L, Musacchio, A, Di Fiore, P.P, Polo, S, Schneider, T.R. | 登録日 | 2005-11-25 | 公開日 | 2006-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Cell, 124, 2006
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4BBN
| NEDD4 HECT-Ub:Ub complex | 分子名称: | E3 UBIQUITIN-PROTEIN LIGASE NEDD4, POLYUBIQUITIN-B | 著者 | Maspero, E, Valentini, E, Mari, S, Cecatiello, V, Polo, S, Pasqualato, S. | 登録日 | 2012-09-27 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of a Ubiquitin-Loaded Hect Ligase Reveals the Molecular Basis for Catalytic Priming Nat.Struct.Mol.Biol., 20, 2013
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4BOS
| Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide | 分子名称: | MAGNESIUM ION, NITRATE ION, OTUD2, ... | 著者 | Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D. | 登録日 | 2013-05-22 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis. Cell(Cambridge,Mass.), 154, 2013
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2AYO
| Structure of USP14 bound to ubquitin aldehyde | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 14 | 著者 | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | 登録日 | 2005-09-07 | 公開日 | 2005-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Embo J., 24, 2005
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2C7N
| Human Rabex-5 residues 1-74 in complex with Ubiquitin | 分子名称: | RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, UBIQUITIN, ZINC ION | 著者 | Penengo, L, Mapelli, M, Murachelli, A.G, Confalioneri, S, Magri, L, Musacchio, A, Di Fiore, P.P, Polo, S, Schneider, T.R. | 登録日 | 2005-11-25 | 公開日 | 2006-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
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1YD8
| COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN | 分子名称: | ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, UBIQUIN | 著者 | Prag, G, Lee, S, Mattera, R, Arighi, C.N, Beach, B.M, Bonifacino, J.S, Hurley, J.H. | 登録日 | 2004-12-23 | 公開日 | 2005-02-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, {gamma}-ear-containing, ADP-ribosylation-factor-binding proteins Proc.Natl.Acad.Sci.USA, 102, 2005
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2DX5
| The complex structure between the mouse EAP45-GLUE domain and ubiquitin | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | 著者 | Hirano, S, Suzuki, N, Slagsvold, T, Kawasaki, M, Trambaiolo, D, Kato, R, Stenmark, H, Wakatsuki, S. | 登録日 | 2006-08-24 | 公開日 | 2006-10-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain Nat.Struct.Mol.Biol., 13, 2006
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2FID
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2FIF
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4ZFR
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4ZFT
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4ZYN
| Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130) | 分子名称: | E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION | 著者 | Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K. | 登録日 | 2015-05-21 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | A Ubl/ubiquitin switch in the activation of Parkin. Embo J., 34, 2015
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