Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin

Summary for 2FIF

DescriptorUbiquitin, Rab5 GDP/GTP exchange factor, SULFATE ION, ... (5 entities in total)
Functional Keywordszinc finger, helix, protein turnover-endocytosis complex, protein turnover/endocytosis
Biological sourceBos taurus (cattle)
Cellular locationCytoplasm O18973
Total number of polymer chains6
Total molecular weight50394.71
Lee, S.,Hurley, J.H. (deposition date: 2005-12-29, release date: 2006-02-07, Last modification date: 2011-07-13)
Primary citation
Lee, S.,Tsai, Y.C.,Mattera, R.,Smith, W.J.,Kostelansky, M.S.,Weissman, A.M.,Bonifacino, J.S.,Hurley, J.H.
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13:264-271, 2006
PubMed: 16462746 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1064
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22440.3%5.8%12.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report