2FIF

Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003677	molecular_function	DNA binding
B	0008270	molecular_function	zinc ion binding
D	0003677	molecular_function	DNA binding
D	0008270	molecular_function	zinc ion binding
F	0003677	molecular_function	DNA binding
F	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 901

Chain	Residue
B	CYS19
B	CYS23
B	CYS35
B	CYS38

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 902

Chain	Residue
D	CYS19
D	CYS23
D	CYS35
D	CYS38

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 903

Chain	Residue
F	CYS23
F	CYS35
F	CYS38
F	CYS19

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 101

Chain	Residue
A	ARG42
A	ARG72
C	LYS11
C	GLU34

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	102
Details	ZN_FING: A20-type => ECO:0000255|PROSITE-ProRule:PRU00451

Chain	Residue	Details
B	ASP13-ARG47
D	ASP13-ARG47
F	ASP13-ARG47
C	ARG72
E	ARG54
E	ARG72

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00451

Chain	Residue	Details
B	CYS19
F	CYS23
F	CYS35
F	CYS38
B	CYS23
B	CYS35
B	CYS38
D	CYS19
D	CYS23
D	CYS35
D	CYS38
F	CYS19

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
A	SER65
C	SER65
E	SER65

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: ADP-ribosylglycine => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
A	GLY76
C	GLY76
E	GLY76

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
A	LYS6
C	LYS27
C	LYS29
C	LYS33
C	LYS48
C	LYS63
E	LYS6
E	LYS11
E	LYS27
E	LYS29
E	LYS33
A	LYS11
E	LYS48
E	LYS63
A	LYS27
A	LYS29
A	LYS33
A	LYS48
A	LYS63
C	LYS6
C	LYS11

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) => ECO:0000255|PROSITE-ProRule:PRU00214

Chain	Residue	Details
A	GLY76
C	GLY76
E	GLY76

---