2C7M

Human Rabex-5 residues 1-74 in complex with Ubiquitin

Summary for 2C7M

Related1AAR 1E0Q 1P3Q 1UZX 1V80 1V81 1WR6 1WRD 1YD8 2BGF 2C7N
DescriptorRAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, UBIQUITIN, ZINC ION, ... (4 entities in total)
Functional Keywordsprotein-binding, ubiquitin complex, ubiquitin binding domain, endocytosis, nuclear protein, polyprotein, ubl conjugation, protein binding
Biological sourceHOMO SAPIENS (HUMAN)
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Total number of polymer chains2
Total molecular weight17427
Authors
Penengo, L.,Mapelli, M.,Murachelli, A.G.,Confalioneri, S.,Magri, L.,Musacchio, A.,Di Fiore, P.P.,Polo, S.,Schneider, T.R. (deposition date: 2005-11-25, release date: 2006-02-15, Last modification date: 2019-05-08)
Primary citation
Penengo, L.,Mapelli, M.,Murachelli, A.G.,Confalonieri, S.,Magri, L.,Musacchio, A.,Di Fiore, P.P.,Polo, S.,Schneider, T.R.
Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.
Cell, 124:1183-1195, 2006
PubMed: 16499958 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2006.02.020
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.27970 6.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report