4B23
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![BU of 4b23 by Molmil](/molmil-images/mine/4b23) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | 分子名称: | 5'-D(*CP*GP*AP*TP*TP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*AP*AP*TP*CP*GP)-3', MAG2, ... | 著者 | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | 登録日 | 2012-07-12 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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1T3N
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![BU of 1t3n by Molmil](/molmil-images/mine/1t3n) | Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP | 分子名称: | MAGNESIUM ION, Primer DNA strand, THYMIDINE-5'-TRIPHOSPHATE, ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. | 登録日 | 2004-04-27 | 公開日 | 2004-07-20 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature, 430, 2004
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465D
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![BU of 465d by Molmil](/molmil-images/mine/465d) | STRUCTURE OF THE TOPOISOMERASE II POISON BOUND TO DNA | 分子名称: | 9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') | 著者 | Adams, A, Guss, J.M, Collyer, C.A, Denny, W.A, Wakelin, L.P. | 登録日 | 1999-04-14 | 公開日 | 1999-08-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the topoisomerase II poison 9-amino-[N-(2-dimethylamino)ethyl]acridine-4-carboxamide bound to the DNA hexanucleotide d(CGTACG)2. Biochemistry, 38, 1999
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3TVB
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![BU of 3tvb by Molmil](/molmil-images/mine/3tvb) | A Highly Symmetric DNA G-4 Quadruplex/drug Complex | 分子名称: | DAUNOMYCIN, DNA (5'-D(*GP*GP*GP*G)-3'), MAGNESIUM ION, ... | 著者 | Clark, G.R, Pytel, P.D, Squire, C.J. | 登録日 | 2011-09-19 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages. Nucleic Acids Res., 40, 2012
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4OO8
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![BU of 4oo8 by Molmil](/molmil-images/mine/4oo8) | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3'), RNA (97-MER) | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2014-01-31 | 公開日 | 2014-02-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Cas9 in complex with guide RNA and target DNA Cell(Cambridge,Mass.), 156, 2014
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1MWJ
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![BU of 1mwj by Molmil](/molmil-images/mine/1mwj) | Crystal Structure of a MUG-DNA pseudo substrate complex | 分子名称: | 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | 著者 | Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H. | 登録日 | 2002-09-30 | 公開日 | 2002-10-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal Structure of a thwarted mismatch glycosylase DNA repair complex Embo J., 18, 1999
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5YQ8
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3UXW
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![BU of 3uxw by Molmil](/molmil-images/mine/3uxw) | Crystal Structures of an A-T-hook/DNA complex | 分子名称: | A-T hook peptide, dodecamer DNA | 著者 | Fonfria-Subiros, E, Acosta-Reyes, F.J, Saperas, N, Pous, J, Subirana, J.A, Campos, J.L. | 登録日 | 2011-12-05 | 公開日 | 2012-05-23 | 最終更新日 | 2013-03-27 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structure of a complex of DNA with one AT-hook of HMGA1. Plos One, 7, 2012
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5YS4
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4B22
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![BU of 4b22 by Molmil](/molmil-images/mine/4b22) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', MAG2, ... | 著者 | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | 登録日 | 2012-07-12 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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3OH6
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![BU of 3oh6 by Molmil](/molmil-images/mine/3oh6) | AlkA Undamaged DNA Complex: Interrogation of a C:G base pair | 分子名称: | 5'-D(*GP*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*CP*AP*TP*TP*CP*AP*TP*GP*TP*C)-3', DNA-3-methyladenine glycosylase 2 | 著者 | Bowman, B.R, Lee, S, Wang, S, Verdine, G.L. | 登録日 | 2010-08-17 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Structure of Escherichia coli AlkA in Complex with Undamaged DNA. J.Biol.Chem., 285, 2010
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6K2J
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3OH9
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![BU of 3oh9 by Molmil](/molmil-images/mine/3oh9) | AlkA Undamaged DNA Complex: Interrogation of a T:A base pair | 分子名称: | 5'-D(*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*TP*TP*CP*AP*TP*GP*T)-3', DNA-3-methyladenine glycosylase 2 | 著者 | Bowman, B.R, Lee, S, Wang, S, Verdine, G.L. | 登録日 | 2010-08-17 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structure of Escherichia coli AlkA in Complex with Undamaged DNA. J.Biol.Chem., 285, 2010
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3OGD
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![BU of 3ogd by Molmil](/molmil-images/mine/3ogd) | AlkA Undamaged DNA Complex: Interrogation of a G*:C base pair | 分子名称: | 5'-D(*CP*AP*(BRU)P*GP*AP*CP*(BRU)P*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*CP*AP*TP*G)-3', DNA-3-methyladenine glycosylase 2 | 著者 | Bowman, B.R, Lee, S, Wang, S, Verdine, G.L. | 登録日 | 2010-08-16 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Escherichia coli AlkA in Complex with Undamaged DNA. J.Biol.Chem., 285, 2010
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6KDV
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![BU of 6kdv by Molmil](/molmil-images/mine/6kdv) | Crystal structure of TtCas1-DNA complex | 分子名称: | CRISPR-associated endonuclease Cas1 2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*GP*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*AP*GP*CP*AP*TP*CP*GP*AP*CP*TP*C)-3') | 著者 | Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y. | 登録日 | 2019-07-02 | 公開日 | 2019-12-18 | 最終更新日 | 2020-05-06 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Crystal structure of Cas1 in complex with branched DNA. Sci China Life Sci, 63, 2020
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7W27
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![BU of 7w27 by Molmil](/molmil-images/mine/7w27) | Crystal structure of BEND3-BEN4-DNA complex | 分子名称: | BEN domain-containing protein 3, DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*GP*CP*GP*TP*GP*GP*GP*TP*C)-3') | 著者 | Zheng, L, Ren, A. | 登録日 | 2021-11-22 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins. Genes Dev., 36, 2022
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4ITD
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![BU of 4itd by Molmil](/molmil-images/mine/4itd) | Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*(C6G)P*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Zhang, F, Suzuki, K, Tsunoda, M, Wilkinson, O, Millington, C.L, Williams, D.M, Morishita, E.C, Takenaka, A. | 登録日 | 2013-01-18 | 公開日 | 2013-05-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing pyrimidine transition mutations Nucleic Acids Res., 41, 2013
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5U33
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![BU of 5u33 by Molmil](/molmil-images/mine/5u33) | Crystal structure of AacC2c1-sgRNA-extended non-target DNA ternary complex | 分子名称: | CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ... | 著者 | Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J. | 登録日 | 2016-12-01 | 公開日 | 2017-01-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease. Cell, 167, 2016
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1MW8
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6F1K
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![BU of 6f1k by Molmil](/molmil-images/mine/6f1k) | Structure of ARTD2/PARP2 WGR domain bound to double strand DNA without 5'phosphate | 分子名称: | CHLORIDE ION, DNA (5'-D(*GP*CP*CP*TP*AP*GP*CP*TP*AP*CP*GP*TP*AP*GP*CP*TP*AP*GP*GP*C)-3'), GLYCEROL, ... | 著者 | Obaji, E, Haikarainen, T, Lehtio, L. | 登録日 | 2017-11-22 | 公開日 | 2018-10-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for DNA break recognition by ARTD2/PARP2. Nucleic Acids Res., 46, 2018
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8AG6
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6FQS
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![BU of 6fqs by Molmil](/molmil-images/mine/6fqs) | 3.11A complex of S.Aureus gyrase with imidazopyrazinone T3 and DNA | 分子名称: | 5-cyclopropyl-8-fluoranyl-7-pyridin-4-yl-imidazo[1,2-a]quinoxalin-4-one, DNA (5'-D(*GP*AP*GP*AP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*TP*CP*TP*T)-3'), DNA gyrase subunit A, ... | 著者 | Bax, B.D, Germe, T, Basque, E, Maxwell, A. | 登録日 | 2018-02-14 | 公開日 | 2018-04-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance. Nucleic Acids Res., 46, 2018
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1NNJ
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![BU of 1nnj by Molmil](/molmil-images/mine/1nnj) | Crystal structure Complex between the Lactococcus lactis Fpg and an abasic site containing DNA | 分子名称: | 5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ... | 著者 | Serre, L, Pereira de Jesus, K, Boiteux, S, Zelwer, C, Castaing, B. | 登録日 | 2003-01-14 | 公開日 | 2003-02-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA. Nucleic Acids Res., 33, 2005
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2ALZ
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![BU of 2alz by Molmil](/molmil-images/mine/2alz) | Ternary Complex of hPoli with DNA and dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*T)-3', ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2005-08-08 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair. Structure, 13, 2005
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8RI3
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![BU of 8ri3 by Molmil](/molmil-images/mine/8ri3) | Crystal structure of transplatin/B-DNA adduct obtained upon 7 days of soaking | 分子名称: | AMMONIA, CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), ... | 著者 | Tito, G, Troisi, R, Ferraro, G, Sica, F, Merlino, A. | 登録日 | 2023-12-18 | 公開日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer. Dalton Trans, 53, 2024
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