1T3N

Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP

Summary for 1T3N

Entry DOI	10.2210/pdb1t3n/pdb
Descriptor	Template DNA strand, Primer DNA strand, polymerase (DNA directed) iota, ... (6 entities in total)
Functional Keywords	protein, dna, dttp, replication-dna complex, replication/dna
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9UNA4
Total number of polymer chains	4
Total formula weight	96507.63
Authors	Nair, D.T.,Johnson, R.E.,Prakash, S.,Prakash, L.,Aggarwal, A.K. (deposition date: 2004-04-27, release date: 2004-07-20, Last modification date: 2018-04-18)
Primary citation	Nair, D.T.,Johnson, R.E.,Prakash, S.,Prakash, L.,Aggarwal, A.K. Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature, 430:377-380, 2004 Cited by PubMed: 15254543 DOI: 10.1038/nature02692 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation