2ALZ

Ternary Complex of hPoli with DNA and dCTP

Summary for 2ALZ

• Entry DOI: 10.2210/pdb2alz/pdb
• Descriptor: 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*T)-3', 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', DNA polymerase iota, ... (6 entities in total)
• Functional Keywords: right handed, dna polymerase, ternary complex, template g. incoming dctp, hoogsteen base pair, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9UNA4
• Total number of polymer chains: 3
• Total formula weight: 49407.04

Authors

Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2005-08-08, release date: 2005-10-25, Last modification date: 2023-08-23)

• Primary citation: Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair.; Structure, 13:1569-1577, 2005; PubMed: 16216587; DOI: 10.1016/j.str.2005.08.010

Experimental method

X-RAY DIFFRACTION (2.5 Å)