PDB: 41454 件ウェブページステータス検索Chemie searchBIRD

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7RBS	The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with human ISG15 分子名称: Papain-like protease, Ubiquitin-like protein ISG15, ZINC ION 著者 Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-06 公開日 2021-09-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
5LZZ	Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5LZY	Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5LZW	Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
5LZX	Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. 登録日 2016-10-02 公開日 2016-11-30 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
8AG6	human MutSalpha (MSH2/MSH6) binding to DNA with a GT mismatch 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (50-MER), DNA mismatch repair protein Msh2, ... 著者 Bruekner, S.R, Sixma, T.K. 登録日 2022-07-19 公開日 2023-01-25 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Unexpected moves: a conformational change in MutS alpha enables high-affinity DNA mismatch binding. Nucleic Acids Res., 51, 2023
6IMQ	Crystal structure of PML B1-box multimers 分子名称: CHLORIDE ION, Protein PML, ZINC ION 著者 Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. 登録日 2018-10-23 公開日 2019-07-31 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. Nat Commun, 10, 2019
5HRY	Computationally Designed Cyclic Dimer ank3C2_1 分子名称: ank3C2_1 著者 Cascio, D, McNamara, D.E, Fallas, J.A, Baker, D, Yeates, T.O. 登録日 2016-01-24 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
5HS0	Computationally Designed Cyclic Tetramer ank1C4_7 分子名称: Ankyrin domain protein ank1C4_7, GLYCEROL, SULFATE ION 著者 McNamara, D.E, Cascio, D, Fallas, J.A, Baker, D, Yeates, T.O. 登録日 2016-01-24 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
5HRZ	Computationally Designed Trimer 1na0C3_3 分子名称: TPR domain protein 1na0C3_3 著者 Cascio, D, McNamara, D.E, Fallas, J.A, Baker, D, Yeates, T.O. 登録日 2016-01-24 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
7T7I	EBV nuclear egress complex 分子名称: Nuclear egress protein 1, Nuclear egress protein 2, ZINC ION 著者 Thorsen, M.K, Heldwein, E.E. 登録日 2021-12-15 公開日 2022-07-06 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.97 Å) 主引用文献 The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism. Plos Pathog., 18, 2022
7S6P	The crystal structure of human ISG15 分子名称: Ubiquitin-like protein ISG15 著者 Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-09-14 公開日 2021-09-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
7L7S	Human mitochondrial chaperonin mHsp60 分子名称: 60 kDa heat shock protein, mitochondrial 著者 Chen, L, Wang, J.C.Y. 登録日 2020-12-30 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. Sci Rep, 11, 2021
7RAA	Designed StabIL-2 seq15 分子名称: Interleukin-2, MAGNESIUM ION 著者 Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C. 登録日 2021-06-30 公開日 2022-03-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Interleukin-2 superkines by computational design. Proc.Natl.Acad.Sci.USA, 119, 2022
7RA9	Designed StabIL-2 seq1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Interleukin-2, PHOSPHATE ION 著者 Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C. 登録日 2021-06-30 公開日 2022-03-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Interleukin-2 superkines by computational design. Proc.Natl.Acad.Sci.USA, 119, 2022
8T5X	Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T) 分子名称: Transthyretin 著者 Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E. 登録日 2023-06-14 公開日 2023-08-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant. J.Am.Chem.Soc., 146, 2024
2XPK	Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases 分子名称: N-[(5R,6R,7R,8S)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDIN-8-YL]-3-SULFANYLPROPANAMIDE, O-GLCNACASE NAGJ 著者 Dorfmueller, H.C, Borodkin, V.S, Schimpl, M, Zheng, X, Kime, R, Read, K.D, van Aalten, D.M.F. 登録日 2010-08-26 公開日 2011-03-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cell-Penetrant, Nanomolar O-Glcnacase Inhibitors Selective Against Lysosomal Hexosaminidases. Chem.Biol, 17, 2010
1MI6	Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome 分子名称: peptide chain release factor RF-2 著者 Rawat, U.B.S, Zavialov, A.V, Sengupta, J, Valle, M, Grassucci, R.A, Linde, J, Vestergaard, B, Ehrenberg, M, Frank, J. 登録日 2002-08-22 公開日 2003-01-14 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (12.8 Å) 主引用文献 A cryo-electron microscopic study of ribosome-bound termination factor RF2 Nature, 421, 2003
7VV9	Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Zheng, Y.Y, Zhou, C. 登録日 2021-11-05 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into Ras regulation by SIN1. Proc.Natl.Acad.Sci.USA, 119, 2022
1O4X	TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT 分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ... 著者 Clore, G.M, Williams, D.C. 登録日 2003-07-17 公開日 2004-01-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J.Biol.Chem., 279, 2004
7AOJ	Plasmoredoxin, a redox-active protein unique for malaria parasites 分子名称: GLYCEROL, Plasmoredoxin 著者 Fritz-Wolf, K, Bathke, J, Rahlfs, S, Becker, K. 登録日 2020-10-14 公開日 2022-04-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites. Curr Res Struct Biol, 4, 2022
7AOO	Plasmoredoxin, a redox-active protein unique for malaria parasites 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, HEXAETHYLENE GLYCOL, ... 著者 Fritz-Wolf, K, Bathke, J, Rahlfs, S, Becker, K. 登録日 2020-10-14 公開日 2022-04-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites. Curr Res Struct Biol, 4, 2022
4UW2	Crystal structure of Csm1 in T.onnurineus 分子名称: CSM1 著者 Jung, T.Y, An, Y, Park, K.H, Lee, M.H, Oh, B.H, Woo, E.J. 登録日 2014-08-08 公開日 2015-03-25 最終更新日 2015-09-23 実験手法 X-RAY DIFFRACTION (2.632 Å) 主引用文献 Crystal Structure of the Csm1 Subunit of the Csm Complex and its Single-Stranded DNA-Specific Nuclease Activity. Structure, 23, 2015
1MQ8	Crystal structure of alphaL I domain in complex with ICAM-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, ... 著者 Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A. 登録日 2002-09-15 公開日 2003-01-14 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003
4F9G	Crystal structure of STING complex with Cyclic di-GMP. 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Transmembrane protein 173 著者 Kabaleeswaran, V, Wu, H. 登録日 2012-05-18 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING. Mol.Cell, 46, 2012

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