1O4X

TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Summary for 1O4X
Descriptor5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', transcription factor Oct-1, ... (4 entities in total)
Functional Keywordsoct1, pou, pous, pouhd, sox2, hmg-box, transcription factors, dna, protein-dna complex, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus: P14859 P48431
Total number of polymer chains4
Total formula weight41446.89
Authors
Clore, G.M.,Williams, D.C. (deposition date: 2003-07-17, release date: 2004-01-27, Last modification date: 2011-07-13)
Primary citationCai, M.,Clore, G.M.,Williams, D.C.
Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279:1449-1457, 2004
PubMed: 14559893
DOI: 110.1074/jbc.M309790200
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation
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PDB entries from 2021-06-16