1O4X
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3' | polymer | 19 | 5816.8 | 1 | |||
| 2 | B (D) | 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3' | polymer | 19 | 5830.8 | 1 | |||
| 3 | C (A) | transcription factor Oct-1 | polymer | 167 | 19081.6 | 1 | UniProt (P14859) Pfam (PF00157) Pfam (PF00046) | Homo sapiens (human) | |
| 4 | D (B) | Transcription factor SOX-2 | polymer | 88 | 10717.7 | 1 | UniProt (P48431) Pfam (PF00505) | Homo sapiens (human) |
Sequence modifications
A: 5 - 167 (UniProt: P14859)
B: 206 - 288 (UniProt: P48431)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| His 3 | - | cloning artifact |
| Met 4 | - | cloning artifact |
| Ala 65 | Cys 363 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | cloning artifact |
| Ser 202 | - | cloning artifact |
| His 203 | - | cloning artifact |
| Met 204 | - | cloning artifact |
| Pro 205 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41446.9 | |
| All* | Total formula weight | 41446.9 |
