8T5X
Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
Summary for 8T5X
| Entry DOI | 10.2210/pdb8t5x/pdb |
| Descriptor | Transthyretin (2 entities in total) |
| Functional Keywords | aggregation, amyloid, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 27614.77 |
| Authors | Ferguson, J.A.,Sun, X.,Leach, B.I.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E. (deposition date: 2023-06-14, release date: 2023-08-02, Last modification date: 2024-01-17) |
| Primary citation | Sun, X.,Ferguson, J.A.,Leach, B.I.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E. Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant. J.Am.Chem.Soc., 146:532-542, 2024 Cited by PubMed: 38134439DOI: 10.1021/jacs.3c10083 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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