8T5X

Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transthyretin	polymer	127	13807.4	2	UniProt (E9KL36) Pfam (PF00576) UniProt (by SIFTS) (P02766)	Homo sapiens (human)
2	C, D (A, B)	water	water		18.0	187	Chemie (HOH)

Sequence modifications

A, B: 1 - 127 (UniProt: E9KL36)

PDB	External Database	Details
Thr 25	Ala 45	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27614.8
All*	Total formula weight	27614.8

*Water molecules are not included.