PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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8IHF	Cryo-EM structure of HCA2-Gi complex with MK6892 分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y. 登録日 2023-02-22 公開日 2023-08-30 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun, 14, 2023
8IHJ	Cryo-EM structure of HCA3-Gi complex with acifran 分子名称: (5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Suzuki, S, Nishikawa, K, Suzuki, H, Fujiyoshi, Y. 登録日 2023-02-22 公開日 2023-08-30 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun, 14, 2023
8J0J	AtSLAC1 8D mutant in closed state 分子名称: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein 著者 Lee, Y, Lee, S. 登録日 2023-04-11 公開日 2023-11-22 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
8J1T	Local refined cryo-EM structure of Omicron BA.5 RBD in complex with 8-9D Fab 分子名称: 8-9D heavy chain, 8-9D light chain, Spike protein 著者 Xiang, Y, Li, R. 登録日 2023-04-13 公開日 2023-11-29 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection. Nat Commun, 14, 2023
8J1E	AtSLAC1 in open state 分子名称: CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein 著者 Lee, Y, Lee, S. 登録日 2023-04-12 公開日 2023-11-22 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
8J6R	Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex 分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. 登録日 2023-04-26 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
8J2F	Human neutral shpingomyelinase 分子名称: HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ... 著者 Zhang, S.S. 登録日 2023-04-14 公開日 2023-12-06 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2). Nat Commun, 14, 2023
8J6Q	Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex 分子名称: (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ... 著者 Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. 登録日 2023-04-26 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
8J6P	Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ... 著者 Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. 登録日 2023-04-26 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.55 Å) 主引用文献 Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
8JMV	Flagellar fibrils from Bacillus amyloliquefaciens 分子名称: Flagella 著者 Cao, Q, Cheng, Y. 登録日 2023-06-05 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM. Nat Commun, 14, 2023
8OIF	Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6 分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... 著者 Wallace, I, Kheewoong, B, Prabu, J.R, Vollrath, R, von Gronau, S, Schulman, B.A, Swatek, K.N. 登録日 2023-03-22 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the ISG15 transfer cascade by the UBE1L activating enzyme. Nat Commun, 14, 2023
8OH7	Structure of A4M4C bound to (KR)4 Solution backbone structure refined by PCS 分子名称: Designed Armadillo repeat protein with four internal modules 著者 Cucuzza, S, Zerbe, O. 登録日 2023-03-20 公開日 2023-12-13 実験手法 SOLUTION NMR 主引用文献 Unexpected dynamics in femtomolar complexes of binding proteins with peptides. Nat Commun, 14, 2023
8KAD	Crystal structure of an antibody light chain tetramer with 3D domain swapping 分子名称: Antibody light chain 著者 Sakai, T, Mashima, T, Kobayashi, N, Ogata, H, Uda, T, Hifumi, E, Hirota, S. 登録日 2023-08-02 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nat Commun, 14, 2023
3ZOY	Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (hexagonal space group) 分子名称: CYTOCHROME C-552, HEME C 著者 Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. 登録日 2013-02-26 公開日 2013-08-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure. Chembiochem, 14, 2013
8ORN	Crystal structure of Xanthomonas campestris pv. campestris LolA-LolB complex 分子名称: Outer-membrane lipoprotein LolB, Outer-membrane lipoprotein carrier protein, SULFATE ION 著者 Furlanetto, V, Divne, C. 登録日 2023-04-14 公開日 2023-07-05 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 LolA and LolB from the plant-pathogen Xanthomonas campestris forms a stable heterodimeric complex in the absence of lipoprotein. Front Microbiol, 14, 2023
8OOG	Crystal structure of human MAT2a with S-Adenosylmethionine and a fragment bound in a novel pocket 分子名称: 6-oxidanyl-1,3-benzoxathiol-2-one, DIMETHYL SULFOXIDE, S-ADENOSYLMETHIONINE, ... 著者 Schimpl, M. 登録日 2023-04-05 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.384 Å) 主引用文献 Combining structural and coevolution information to unveil allosteric sites. Chem Sci, 14, 2023
8ONQ	Structure of the amyloid-forming peptide Ac-EFIAWL from human GLP-1 分子名称: Peptide Ac-EFIAWL from hGLP-1 著者 Durvanger, Z. 登録日 2023-04-03 公開日 2023-08-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8P0P	Crystal structure of AaNGT complexed to UDP-2F-Glucose 分子名称: Adhesin, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE 著者 Piniello, B, Macias-Leon, J, Rovira, C, Hurtado-Guerrero, R. 登録日 2023-05-10 公開日 2023-09-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase. Nat Commun, 14, 2023
8OSH	AAA+ motor subunit ChlI of magnesium chelatase, pentamer spring-washer-like conformation 分子名称: Magnesium-chelatase subunit ChlI 著者 Shvarev, D, Moeller, A. 登録日 2023-04-18 公開日 2023-09-06 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis. Mbio, 14, 2023
8P5S	Crystal structure of the homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum 分子名称: 2-oxoglutarate dehydrogenase E1/E2 component, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYL COENZYME *A, ... 著者 Yang, L, Boyko, A, Bellinzoni, M. 登録日 2023-05-24 公開日 2023-08-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.459 Å) 主引用文献 High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase. Nat Commun, 14, 2023
8P97	BtuB3G3 bound to cyanocobalamin with disordered EL8 分子名称: CYANOCOBALAMIN, Putative surface layer protein, TonB-dependent receptor 著者 Silale, A, Abellon-Ruiz, J, van den Berg, B. 登録日 2023-06-05 公開日 2023-08-16 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B 12 uptake in gut Bacteroides. Nat Commun, 14, 2023
4COK	Functional and Structural Characterization of Pyruvate decarboxylase from Gluconoacetobacter diazotrophicus 分子名称: MAGNESIUM ION, PYRUVATE DECARBOXYLASE, SULFATE ION, ... 著者 vanZyl, L.J, Schubert, W.-D, Tuffin, M, Cowan, D.A. 登録日 2014-01-29 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure and Functional Characterization of Pyruvate Decarboxylase from Gluconacetobacter Diazotrophicus. Bmc Struct.Biol., 14, 2014
4BWA	PylRS Y306G, Y384F, I405R mutant in complex with adenylated norbornene 分子名称: 1,2-ETHANEDIOL, Adenylated Norbornene, DI(HYDROXYETHYL)ETHER, ... 著者 Schneider, S, Vrabel, M, Gattner, M.J, Fluegel, V, Lopez-Carillo, V, Carell, T. 登録日 2013-07-01 公開日 2013-07-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural Insights Into Incorporation of Norbornene Amino Acids for Click Modification of Proteins Chem.Bio.Chem., 14, 2013
5TFX	New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase 分子名称: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3-benzoxazol-2-yl)benzamide, ... 著者 Peat, T.S, Supuran, C. 登録日 2016-09-26 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors. Org. Biomol. Chem., 14, 2016
7EIU	Crystal structure of Mei2 RRM3 in complex with 8mer meiRNA 分子名称: GLYCEROL, Meiosis protein mei2, RNA (5'-R(P*UP*UP*CP*UP*GP*C)-3') 著者 Shen, S.Y, Lv, M.Q. 登録日 2021-03-31 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Structural insights reveal the specific recognition of meiRNA by the Mei2 protein. J Mol Cell Biol, 14, 2022

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