5TFX
New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase
Summary for 5TFX
| Entry DOI | 10.2210/pdb5tfx/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase mimic, inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29763.89 |
| Authors | Peat, T.S.,Supuran, C. (deposition date: 2016-09-26, release date: 2017-08-09, Last modification date: 2023-10-04) |
| Primary citation | Angeli, A.,Peat, T.S.,Bartolucci, G.,Nocentini, A.,Supuran, C.T.,Carta, F. Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors. Org. Biomol. Chem., 14:11353-11356, 2016 Cited by PubMed: 27892589DOI: 10.1039/c6ob02299e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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