4COK

Functional and Structural Characterization of Pyruvate decarboxylase from Gluconoacetobacter diazotrophicus

Summary for 4COK

• Entry DOI: 10.2210/pdb4cok/pdb
• Descriptor: PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: lyase
• Biological source: GLUCONACETOBACTER DIAZOTROPHICUS PAL 5
• Total number of polymer chains: 2
• Total formula weight: 119479.00

Authors

vanZyl, L.J.,Schubert, W.-D.,Tuffin, M.,Cowan, D.A. (deposition date: 2014-01-29, release date: 2014-10-01, Last modification date: 2023-12-20)

Primary citation

Van Zyl, L.J.,Schubert, W.,Tuffin, M.I.,Cowan, D.A.
Structure and Functional Characterization of Pyruvate Decarboxylase from Gluconacetobacter Diazotrophicus.
Bmc Struct.Biol., 14:21-, 2014

PubMed Abstract: Bacterial pyruvate decarboxylases (PDC) are rare. Their role in ethanol production and in bacterially mediated ethanologenic processes has, however, ensured a continued and growing interest. PDCs from Zymomonas mobilis (ZmPDC), Zymobacter palmae (ZpPDC) and Sarcina ventriculi (SvPDC) have been characterized and ZmPDC has been produced successfully in a range of heterologous hosts. PDCs from the Acetobacteraceae and their role in metabolism have not been characterized to the same extent. Examples include Gluconobacter oxydans (GoPDC), G. diazotrophicus (GdPDC) and Acetobacter pasteutrianus (ApPDC). All of these organisms are of commercial importance.

PubMed: 25369873
DOI: 10.1186/S12900-014-0021-1

Experimental method

X-RAY DIFFRACTION (1.69 Å)